Agenda 18mar2019 PhD Defense Niels Cremers

Niels Cremers Cytoprotective mechanisms, palatogenesis, and wound repair

The research postulated that the balance between harmful and protective factors during pregnancy influences the chance of developing congenital abnormalities such as CL/P and the biological processes during wound repair.

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Niels Cremers Cytoprotective mechanisms, palatogenesis, and wound repair

A cleft lip and or palate (CL/P) can lead to aesthetic and functional problems, including speech and swallowing. Despite surgical closure of the gap, problems often persist because of scar formation. We postulated that the balance between harmful and protective factors during pregnancy influences the chance of developing congenital abnormalities such as CL/P and the biological processes during wound repair. Our experiments in mice showed that a shortage of protective mediators results in a higher chance of malformations during births and results in delayed wound healing. This suggests that activating protective signals may promote normal pregnancy and improve wound repair.

Date, time and location PhD defense

  • Date: 18 March 2019
  • Time: 16:30 hrs
  • Location: Radboud Universiteit, Academiezaal Aula, Comeniuslaan 2

Biography

Niels Cremers obtained his Masters’ degree in Biomedical Sciences in 2010 from the Radboud University. He excels in the development of novel therapies to improve wound healing and is aiming to translate science into clinical application.

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Biography

Niels Cremers obtained his Masters’ degree in Biomedical Sciences in 2010 from the Radboud University. He excels in the development of novel therapies to improve wound healing and is aiming to translate science into clinical application. Currently, he is working as a research associate at Triticum where he investigates the use of honey-based wound care products.


Promotor

  • Promotor(s): Prof. C.E.L. Carels and Prof. A.M. Kuijpers-Jagtman
  • Co-promotor(s): F.A.D.T.G. Wagener, PhD

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