Matteo Perino Molecular regulation of Polycomb complexes in mouse embryonic stem cellsEvery multicellular organism, even the simplest, has the ability to generate cells with very different, specialised functions using the same genetic information. This is achieved via epigenetic regulation which checks how, when and which part of this "blueprint" is used. Via a complex system, environmental and genetic signals are integrated to generate cells with different identities and functions from the same DNA. All this is done in complete harmony to ensure the formation of a complete organism. Matteo Perino investigated the molecular regulation of the protein complex Polycomb Repressive Complex 2 in embryonic cells of mice and the embryonic development of the frog Xenopus Tropicalis.
Date, time and location PhD defense
- Date: 27 May 2019
- Time: 10:30 hrs
- Location: Radboud Universiteit, Academiezaal Aula, Comeniuslaan 2
Matteo Perino (1988, Rome, Italy) studied Biotechnology at the University of Roma Tor Vergata and obtained a Master’s in Medical, Molecular and Cellular Biotechnology at Università Vita-Salute S.Raffale (Milan). Since April 2018, he has been a postdoctoral researcher at EMBL where he studies the regulation of zygotic genome activation in Drosophila.
- Promotor(s): Prof. G.J.C. Veenstra