Agenda PhD defense Marije Behet

Marije Behet Functional antibodies play an important role in immunity against malaria

Malaria remains one of the most common and severe infectious diseases worldwide. The disease is a mosquito-borne infectious disease and caused by Plasmodium parasites, with Plasmodium falciparum being the deadliest species.

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Marije Behet Functional antibodies play an important role in immunity against malaria

Malaria remains one of the most common and severe infectious diseases worldwide. The disease is a mosquito-borne infectious disease and caused by Plasmodium parasites, with Plasmodium falciparum being the deadliest species.The emergence of drug-resistant parasites and insecticide-resistant mosquitoes are threatening malaria control efforts, underscoring the need for a highly effective malaria vaccine. A major stumble block for the development of an effective anti-malarial vaccine is our incomplete understanding of protective immune responses to malaria. This thesis demonstrates that antibodies that are acquired following experimental or natural exposure to malaria parasites play an important role in our defense against Plasmodium falciparum malaria parasites. These antibodies recognize early stages of malaria parasites in the human host and can prevent malaria infection. Multiple antibody-mediated mechanisms likely contribute to protective anti-malarial immunity.

 

Date, time and location PhD defense

  • Date: 22 November 2018
  • Time: 12:30 hrs
  • Location: Radboud Universiteit, Academiezaal Aula, Comeniuslaan 2

Biography

Marije Behet (1987) graduated bene meritum from Radboud University in Nijmegen (Master’s degree in Biomedical Sciences).

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Biography

Marije Behet (1987) graduated bene meritum from Radboud University in Nijmegen (Master’s degree in Biomedical Sciences). She carried out the research in this thesis at the Department of Medical Microbiology (Medical Parasitology) of Radboud university medical center, within the Radboud Institute for Molecular Life Sciences.
 


Promotor

  • Promotor(s): Prof. R. Sauerwein
  • Co-promotor(s): A. Scholzen, PhD

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