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Donders Institute for Brain Cognition and Behaviour News
News items related to the Donders Center for Medical Neuroscience.
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Radboudumc to lead research team into tackling future pandemics NWO funds complexity research on pandemics

5 August 2021

The Radboudumc is going to lead a study on how to deal with future pandemics, together with Radboud University and the University of Amsterdam. Rick Quax from the Informatics Institute/IAS is involved in this project.

Treatment of brain diseases at risk if neuroscientists can no longer conduct their research

5 August 2021

In order to treat brain diseases such as depression, Alzheimer's or ADHD, more research into the brain is needed.

More variants TLR7 gene found in young healthy men with severe Covid-19 Screening and accelerated vaccination for TLR7 immunodeficiency

3 August 2021

Spanish-Dutch research has revealed two new mutations in the TLR7 gene in healthy young men who became seriously ill with severe Covid-19.

Nijmegen literally puts Digital Health on the map Flourishing ecosystem gets its own interactive overview

22 July 2021

Digital Health is thriving in the Nijmegen region, where it contributes to better care and health and also creates jobs. To bring developers and end users even closer together, The Economic Board and the Radboudumc are introducing the Interactive Digital Health map.

ZonMw funding for PSIDER program

14 July 2021

Michiel Vermeulen, Klaas Mulder and Nael Nadif Kasri receive funding from ZonMw for a collaborative project to develop a stem cell based model to study early human embryogenesis.

VIDI grants for researchers of Radboud university medical center

14 July 2021

Several Radboudumc researchers have been awarded a VIDI grant by the Dutch Organisation for Scientific Research (NWO). They each receive a sum of 800,000 euros, which they will use over the next five years to develop their own innovative line of research and to set up a research group.

Sonlicromanol seems promising for certain cancers Khondrion announces publication in PLOS ONE of new research

13 July 2021

Khondrion announces publication in PLOS ONE of new research showing normalisation of prostate cancer stem cell mPGES-1 overexpression and inhibition of cancer spheroid growth by sonlicromanol’s active metabolite.

Newborn screening in sight through the discovery of novel disease biomarkers by new technique

8 July 2021

To identify new biomarkers that can be used in the newborn screening protocol, also known as the neonatal heel prick, Karlien Coene and colleagues joined forces with scientists at the Radboud University’s FELIX laser laboratory. They published their findings in The Journal of Clinical Investigation.

Radboud Pluim for Myrthe Swaak

8 July 2021

''Extraordinary accomplishments, strong commitment and a positive and constructive attitude” were the words used to praise senior communications advisor for science, Myrthe Swaak, when she received the Radboud Pluim.

Next Generation cytogenetics is on its way Does Optical Genome Mapping turn cytogenetics upside down?

7 July 2021

Dutch-French research shows that Optical Genome Mapping (OGM) detects abnormalities in chromosomes and DNA very quickly, effectively and accurately.

Radboudumc receives prestigious Edmond J. Safra Fellowship

5 July 2021

Fellowship to train a new movement disorder clinician-researcher (a neurologist with additional education and expertise in Parkinson’s and related diseases)

ZonMw Open Competition Grants for several Radboud researchers

15 June 2021

Four teams including researchers from Radboudumc and Radboud University receive a ZonMw Open Competion grant. Each proposal has a maximum budget of 750K euros.

Human microbiome could shed light on higher morbidity rate in minoritized populations The link between environmental inequities and disease may lie in the gut

15 June 2021

A study published in PNAS is the first to explicitly address the gut microbiome as a pathway to understanding how environmental inequities could lead to health disparities.

New ultra-high field MRI system available for Radboudumc and Radboud University

10 June 2021

Recently, the Hahn institute in Essen has received a new heart: a 20-ton ultra-high-field MRI scanner from Siemens Healthcare with a magnetic field strength of 7 Tesla. The new CE-approved scanner is ready for business, and projects on body and brain imaging are starting up.

On the prevalence of cerebral amyloid angiopathy a systematic review and meta-analysis

10 June 2021

Published in ‘Alzheimers and Dementia’, researchers at Radboudumc performed a systematic review and meta-analysis on the prevalence of Cerebral Amyloid Angiopathy. They scrutinized and analyzed 170 publications, comprising publications using either a neuroimaging or a neuropathological approach.

Retina-on-chip modeling and treating eye diseases in a dish

10 June 2021

Alex Garanto, together with Anneke den Hollander and Andries van der Meer (UTwente) have received 1,17M€ to develop a retina-on-chip model to improve our understanding in eye diseases and to develop treatments against them.

Radboud Pluim for Dagmar Eleveld-Trancikova Policy advisor of the three research institutes

8 June 2021

Radboudpluim for research policy adviser Dagmar Eleveld-Trancikova.

Gut microbiota alleviates effects of stress on cognition

3 June 2021

Researchers from the Radboudumc and Donders Institute have shown that the gut microbiota is involved in the protecting effects of probiotics on cognitive performance in acute stress circumstances. Their results are now published in Translational Psychiatry.

European research project raises hopes in fight against rare diseases Solve-RD successfully established an innovative approach to jointly re-analyze genomic and phenotypic data from unsolved rare disease patients

1 June 2021

For the first time in Europe hundreds of rare disease experts team up to actively share and jointly analyze existing data from unsolved rare disease patients.

Families with a child with ADHD can benefit from mindfulness training

27 May 2021

Publication in Journal of Child Psychology and Psychiatry

Innovative therapy developed for the future treatment of hereditary (deaf)blindness

26 May 2021

Researchers from the department of Otorhinolaryngology, headed by Erwin van Wijk, developed a novel therapeutic strategy to halt the progression or to prevent vision loss in patients as a consequence of USH2A exon 13 mutations.

First volunteers vaccinated with Radboudumc malaria vaccine

20 May 2021

Today a new vaccine against malaria, largely developed in Nijmegen, is being tested for the first time in volunteers at Radboudumc.

The crucial role of brain network efficiency in gait in patients with small vessel disease

20 May 2021

In the recently published work in NeuroImage: Clinical, from the Department of Neurology, Radboudumc researcher Mengfei Cai and his colleagues investigated the potential mechanisms of gait decline.

The ongoing COVID-19 pandemic not only impacts physical healthcare

20 May 2021

Arnt Schellekens, in collaboration with the international Network of Early Career Professionals working in Addiction Medicine published results of an international inventory in Frontiers in Psychiatry, in order to identify the impact of the coronavirus pandemic on addiction care at a country level.

Intensive writing week - online from Radboud in'to Languages

19 May 2021

This course is for early-career researchers, such as PhD candidates and postdocs, who are writing an article or thesis.

Call for entries Eppendorf & Science Prize for Neurobiology 2021

18 May 2021

Are you or one of your colleagues doing great research? If so, then we encourage you to apply for the prestigious Eppendorf & Science Prize for Neurobiology.

Detecting impaired respiratory muscle structure and function using ultrasound and magnetic resonance

17 May 2021

Jeroen van Doorn and colleagues published a comprehensive review on imaging of the respiratory muscles in neuromuscular disorders in the European Respiratory Journal

Call Dutch L’Oréal UNESCO for Women in Science fellowships

12 May 2021

The Fondation L’Oréal and UNESCO invite you to nominate eminent women scientists for the 2022 L’Oréal-UNESCO For Women in Science International Awards. Deadline 31 May 2021.

Four NWO Open Competition Grants for Radboud researchers

11 May 2021

Four researchers from Radboud University and Radboudumc receive a NWO Open Competion grant from the NWO Domain Social Sciences and Humanities.

Miniaturized microfluidic platform for automated epigenetic profiling

6 May 2021

Together with Fluidigm, a US-based company focusing on microfluidics, the team of Hendrik Marks publishes in Genome Research the development of a powerful plug and play ChIP-seq platform for minute amount of cells, such as embryonic specimens or small biopsies.

Not treating high blood pressure in the elderly a dangerous misconception

3 May 2021

Not treating high blood pressure in the elderly and people with dementia can lead to more heart and brain infarctions. That is the conclusion of clinical geriatrician Jurgen Claassen. He co-wrote a review article on the mechanism of brain blood flow that challenges these incorrect assumptions.

Foundation Fighting Blindness Awards 1.4 million dollars for Rob Collin and Carel Hoyng

29 April 2021

Two researchers from the Radboudumc have received a prestigious award from the Translational Research Acceleration Program of the Foundation Fighting Blindness USA.

Radboud university medical center appoints thirteen female professors

29 April 2021

Their fields of expertise cover the entire (bio-)medical field, ranging from fundamental and translational to clinical research, education and patient care.

Higher education does not influence how the brain ages

28 April 2021

Contrary to popular belief, a new study from the Lifebrain consortium at the University of Oslo finds that higher education does not slow brain aging. Radboudumc and Donders Institute researcher Rogier Kievit is also part of this study.

Royal decorations for Nicoline Hoogerbrugge, Jolanda de Vries, Koos van der Velden and Jan Buitelaar

28 April 2021

Nicoline Hoogerbrugge, Jolanda de Vries, Koos van der Velden and Jan Buitelaar are appointed by His Majesty as Knight in the Order of the Dutch Lion, a highly prestigious decoration on 26 April 2021.

Sleep researcher Martin Dresler new member FENS-Kavli Network of Excellence

22 April 2021

Martin Dresler has been appointed member of the prestigious FENS-Kavli Network of excellence. The sleep researcher will be one of the 30 members of the network, of which 15 members are newly selected every 2 years.

Grants for science communication at Radboudumc

22 April 2021

Scientists at the Radboudumc have received two KNAW grants, each worth 10,000 euros, for science communication. With the new fund, KNAW underlines importance of making science accessible.

Brain region controls pathological aggression but leaves context-appropriate aggresion intact

21 April 2021

In recent work published in Current Biology, researchers from Radboudumc and Donders Institute, as well as other international collaborators, showed that in mice, anterior cingulate cortex dials down excessive aggression, but leaves context-appropriate aggression intact.

Lack of evidence for genetic defects in previously implicated gene in patients with male infertility

20 April 2021

In a letter to Cell, researchers from the department of Human Genetics at Radboudumc have raised concerns about the claimed role of PIWIL1 D-box region mutations in human male infertility in an earlier publication in the same journal.

Towards the real-time monitoring of patient resilience

20 April 2021

Research in the Department of Geriatrics has explored how quantifying a patient’s physical resilience – the ability to resist functional decline and recover physical health following a stressor – can support clinical intuition and decision-making. Results are published in Experimental Gerontology.

New way of diagnostics detects 'undetectable' genetic defects

15 April 2021

Research provides guidance for global application

Vici grant for Michiel Vermeulen Reading the epitranscriptome

15 April 2021

Michiel Vermeulen, theme Cancer development and immune defense, has been awarded a Vici grant from the Netherlands Organisation for Scientific Research (NWO), one of the largest personal scientific awards in the Netherlands.

COVID-19 regulations for nursing homes have varying effects

14 April 2021

On May 11th 2020, the Dutch Government allowed 26 nursing homes to welcome one visitor per resident, after two months of lockdown. An in-depth Radboudumc study monitored the feasibility of the regulations and the impact on the well-being of residents, their visitors, and healthcare staff.

ADHD-related alterations in brain organization based on different brain profiles

14 April 2021

Structural differences between the brains of people with and without ADHD are extensively reported. In accordance with earlier (ENIGMA) studies, and using a large cohort, a newly published study builds upon these by showing differences in brain organization that is based on different brain profiles.

Miljoenen voor kennis- en investeringsconsortium op het gebied van AI

14 April 2021

Een kennis- en investeringsconsortium met het Radboudumc heeft acht miljoen euro subsidie gekregen om innovatie op het gebied van Artificial Intelligence (AI) versneld naar de markt te brengen.

Genetische pleister ‘remt’ blindheid in patiënten met Usher syndroom Leidse ProQR bouwt onderzoek Radboudumc verder uit

14 April 2021

Het Leidse biotechbedrijf ProQR Therapeutics presenteerde deze week positieve resultaten van een klinische fase I/II studie met het molecuul QR-421a, een molecuul dat in de vroegste fase is ontwikkeld door onderzoekers van het Radboudumc

Seven million cases of Parkinson's disease The fastest growing brain disease in the world

13 April 2021

Over seven million people worldwide have Parkinson's disease, and it is the fastest growing brain disease in the world. Different forms of personalized treatment plans are needed. This is what Radboudumc neurologist Bas Bloem writes in a review article published in The Lancet.

Academic Alliance Fund (AAF) grant for Florian Krause

8 April 2021

He received 100 kEuro for their project “Getting Trauma Under Control: Learning to Self-Regulate PTSD Brain Networks Through Prospective Neurofeedback Training".

Current overview of intriguing RNA therapies

8 April 2021

In an article in EMBO Molecular Medicine, researchers from Radboudumc, together with European colleagues, provide an up-to-date overview of the (im)possibilities of these intriguing RNA therapies.

Research on treatment for therapy-resistant obsessive-compulsive disorder

1 April 2021

The Radboudumc is participating in a study, led by Amsterdam UMC, into a new, promising treatment for therapy-resistant obsessive-compulsive disorder. A sum of 2.8 million euros has been made available, with several other hospitals and mental healthcare institutions also participating.

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