People Francisco Jesus Arjona Madueno

Contact

Francisco Jesús Arjona Madueño PhD

+31 (0)24 361 42 02
Contact

Francisco Arjona Madueño postdoc

My current investigation line at the Department of Physiology in the Radboud university medical center focuses on the identification and characterization of new molecular players (transporters, channels and regulatory factors) involved in renal Magnesium (Mg2+) handling.

read more

Francisco Arjona Madueño postdoc

One of our biggest challenges in nephrology is the functional characterization of proteins expressed in the different segments of the nephron in health and disease. Given the high prevalence of hypomagnesemia in hospitalized patients and the symptoms associated (i.e. cardiovascular and neurological disorders), research on the (patho)mechanisms that yield hypomagnesemia is needed. Consequently, my current investigation line at the Department of Physiology in the Radboud university medical center focuses on the identification and characterization of new molecular players (transporters, channels and regulatory factors) involved in renal Magnesium (Mg2+) handling since the kidney is the main organ regulating Mg2+ homeostasis. In this regard, my research is particularly oriented to the elucidation of the pathophysiological implications of these new molecular players when they are dysfunctional. Thus, the molecular etiology of Mg2+ reabsorption disorders in the kidney of patients with symptomatic hypomagnesemia can be established.

Field of study

Physiology

Radboud Institute for Molecular Life Sciences

Our main aim is to achieve a greater understanding of the molecular mechanisms of disease. By integrating fundamental and clinical research, we obtain multifaceted knowledge of (patho)physiological processes. read more
  • Go to