Juan Pablo Rigalli postdocJuan Pablo Rigalli (b. 1985) obtained his Master's degree in Biotechnology (2009) and his PhD in Biological Sciences (2013) at Rosario University in Argentina. During this early phase of his career he worked in the field of molecular pharmacology and studied the potential of therapeutic agents like the trypanocidal benznidazole to act as a perpretator of drug-drug interactions, specially by regulation of ATP binding cassette (ABC) drug transporters. He has been always interested in the molecular mechanisms underlying pharmacological effects and interactions. In 2015 he moved to Heidelberg (Germany) where he was awarded a research grant from the German Research Foundation (DFG) to evaluate the interaction between human papillomaviruses, ABC transporters and multidrug resistance in head and neck squamous cell carcinoma. In January 2018 he joined the group of ion transport.
His projects are:
- establishing a model of human kidney organoids to study patho(physiological) processes related to the electrolyte balance
- evaluating the role of ATP as a signalling molecule in the modulation of renal electrolyte handling