Cerebral perfusion in neurosurgeryThis research group explores the feasibility and diagnostic accuracy of cerebral perfusion imaging in neurosurgery. We compare several techniques, including Magnetic Resonance (MR) and Flat Panel Computed Tomography, and develop new applications for cerebral perfusion imaging in the Hybrid-OR.
Aims of this research groupOur research group aims to:
- Summarize the available evidence on diagnostic accuracy in cerebral perfusion imaging by conducting a systematic review, comparing FP-CT, CTP and MRP.
- Identify the optimal technique for intra-operative applications and image-guided interventions in the Hybrid-OR.
- Explore the feasibility, added value and cost-effectiveness of cerebral perfusion imaging in neurosurgery.
- Develop new applications for cerebral perfusion imaging in the Hybrid-OR.
Discoveries of this research groupA systematic review comparing FP-CT cerebral perfusion imaging with CTP and MRP in diagnostic accuracy showed very little evidence, mostly pilot- and feasibility studies in subjects with cerebrovascular disease.
All studies were set outside the Hybrid-OR in the angiographic room and half of the studies were conducted in animals. A few small studies with moderate quality assessments compared FP-CTP with CTP and showed high diagnostic accuracy in patients with cerebrovascular disease and good correlations between both techniques.
Research within MITeCWe explore the feasibility and diagnostic accuracy of FP-CT and MR in cerebral perfusion imaging in the Hybrid-OR. After our systematic review, we will conduct a pilot study that compares FP-CT and MR in cerebral perfusion imaging in patients scheduled for neurosurgery.
Both techniques are available at our Hybrid-OR and all neurosurgical procedures will be performed at our MITeC.
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