Establishing physiological biomarkers of perioperative stress

We conduct imaging and cognitive research right at the intersection between clinical psychiatry and cognitive neuroscience with a focus on emotional and non-emotional forms of declarative memory that also play a role in development and maintenance of stress-related mental disorders.

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People Jurgen Futterer Establishing physiological biomarkers of perioperative stress

Establishing physiological biomarkers of perioperative stress

This research group conducts imaging and cognitive research right at the intersection between clinical psychiatry and cognitive neuroscience.

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Research group leader

Jurgen Futterer MD PhD

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Aims of this research group

Our aim is to research vulnerability of stress-related mental disorders across the life span by conducting several studies related to the neurocognitive impact of on the one hand, childhood adversity and acute stress and on the other hand, the effects of healthy and pathological aging.

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Aims of this research group

Our aim is to research vulnerability of stress-related mental disorders across the life span by conducting several studies related to the neurocognitive impact of on the one hand, childhood adversity and acute stress and on the other hand, the effects of healthy and pathological aging.

Moreover, we aim to extend our stress-related research in collaboration with researchers from Radboudumc’s cancer themes to investigate impact of acute stress in hematology oncology and prostate cancer.
 

Discoveries of this research group

This research group conducts research at the intersection between clinical psychiatry and cognitive neuroscience focusing on declarative memory. We used structural and functional magnetic resonance imaging methods next to experimental psychology.

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Discoveries of this research group

This research group conducts research at the intersection between clinical psychiatry and cognitive neuroscience focusing on declarative memory. We used structural and functional magnetic resonance imaging methods next to experimental psychology.
 
One major achievement was to elucidate the neurobiology of cognitive schemas creating and maintaining depression, taking into account the impact of acute and early environmental adversity in adulthood and aging.
 
Another major achievement was to unravel the neurobiology of depressive subtypes and chronic depression in particular and set-up a neuromodulation outpatient clinic (led by P. van Eijndhoven) that develops and tests new forms of rTMS in depression.
 
Finally, our EU regional funding has allowed us to develop new cognitive interventions that are tested in currently ongoing clinical trials both in depression as well as stress-related adversity in cancer patients in Nijmegen as well as hospitals in Kleve and Essen.

Research within MITeC

This group assesses the subjective stress response during MR guided prostate biopsy and elucidate potential mediating influences.

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Research within MITeC

In collaboration with Dr. Jurgen Fütterer from MITeC and Dr. Nils Kohn from the Department of Cognitive Neuroscience this group assesses the subjective stress response during MR guided prostate biopsy and elucidate potential mediating influences of cognitive and affective factors, long term stress exposure and stress-related brain connectivity dynamics.

Team

Radboudumc Technology Center Translational neuroscience

The Translational Neuroscience Unit enables researchers to explore the neural basis of cognition, emotion and behavior, through integrated systems neuroscience facilities with a translational twist.

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MITeC Connected operating rooms, for advancing innovation in patient care

MITeC offers unique consulting services and expertise to incorporate newly developed medical technology innovations and accelerate their success rate.

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Donders Institute for Brain, Cognition and Behaviour

As part of the Donders Institute for Brain, Cognition and Behaviour – the Donders Center for Medical Neuroscience is devoted to understanding the mechanistic underpinnings of human cognition and behavior in health and disease. read more