Establishing physiological biomarkers of perioperative stress
This research group conducts imaging and cognitive research right at the intersection between clinical psychiatry and cognitive neuroscience.read more
Aims of this research group
Our aim is to research vulnerability of stress-related mental disorders across the life span by conducting several studies related to the neurocognitive impact of on the one hand, childhood adversity and acute stress and on the other hand, the effects of healthy and pathological aging.read more
Aims of this research groupOur aim is to research vulnerability of stress-related mental disorders across the life span by conducting several studies related to the neurocognitive impact of on the one hand, childhood adversity and acute stress and on the other hand, the effects of healthy and pathological aging.
Moreover, we aim to extend our stress-related research in collaboration with researchers from Radboudumc’s cancer themes to investigate impact of acute stress in hematology oncology and prostate cancer.
Discoveries of this research groupThis research group conducts research at the intersection between clinical psychiatry and cognitive neuroscience focusing on declarative memory. We used structural and functional magnetic resonance imaging methods next to experimental psychology.
One major achievement was to elucidate the neurobiology of cognitive schemas creating and maintaining depression, taking into account the impact of acute and early environmental adversity in adulthood and aging.
Another major achievement was to unravel the neurobiology of depressive subtypes and chronic depression in particular and set-up a neuromodulation outpatient clinic (led by P. van Eijndhoven) that develops and tests new forms of rTMS in depression.
Finally, our EU regional funding has allowed us to develop new cognitive interventions that are tested in currently ongoing clinical trials both in depression as well as stress-related adversity in cancer patients in Nijmegen as well as hospitals in Kleve and Essen.
Research within MITeCIn collaboration with Dr. Jurgen Fütterer from MITeC and Dr. Nils Kohn from the Department of Cognitive Neuroscience this group assesses the subjective stress response during MR guided prostate biopsy and elucidate potential mediating influences of cognitive and affective factors, long term stress exposure and stress-related brain connectivity dynamics.
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