People Mangala Srinivas Multiscale Imaging

Multiple types om imaging

This group focuses on new contrast agents for multiple types of imaging such as 1H and 19F magnetic resonance imaging (MRI), positron emission tomography (PET), computed tomography (CT), single photon emission CT (SPECT), bioluminescence, ultrasound, optoacoustics and fluorescence, simultaneously.

Research group leader

Mangala Srinivas PhD
assistant professor

+31 (0)24 361 05 56
contact

Aims

The particles contain liquid perfluorocarbons with a metal chelate in a polymer matrix, resulting in a unique structure that we are actively studying through different types of NMR and even Small Angle Neutron Scattering (SANS), among others. 

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Aims

The particles contain liquid perfluorocarbons with a metal chelate in a polymer matrix, resulting in a unique structure that we are actively studying through different types of NMR and even Small Angle Neutron Scattering (SANS), among others. 

We are also developing the nanoparticles to comprehensively monitor modern personalised medicine, such as cell therapies, targeted therapies and theranostics. We are involved with all aspects of this work, including label development and formulation for human (GMP) and preclinical use, cell handling and labeling, in vivoanimal models, imaging, development for clinical application and upscaling production. The work is inherently multidisciplinary, and we work with immunologists, chemists, physicists and physicians, with a clinical trial with melanoma patients in progress.


Interesting links

Team

Radboud Institute for Molecular Life Sciences

Our main aim is to achieve a greater understanding of the molecular mechanisms of disease. By integrating fundamental and clinical research, we obtain multifaceted knowledge of (patho)physiological processes. read more