Biomechanics and Reconstruction of deformities and defects of the musculoskeletal systemThe goal of orthopedic surgery is to reconstruct deformities and defects of the musculoskeletal system. Our research focuses on the external loads applied to the musculoskeletal system, and how these loads influence the reconstructions.
Research group leader
Nico Verdonschot PhD
+31 (0)24 361 33 66
AimsThe Orthopaedic Research Laboratory (ORL) aims to determine the loads acting on the musculoskeletal system during activities of daily living, and how orthopaedic surgery influences these loads and joint kinematics. For this purpose, computational analyses (e.g. finite element analysis, musculoskeletal modelling) are combined with in vitro testing, and medical imaging ((dynamic) CT and MRI). These tools are used to better predict the outcome of interventions, to further improve the quality of orthopaedic care.
To reliably and accurately translate these interventions to the operating room, the ORL works together with MITeC and the 3D Lab to develop surgical guidance systems, navigated surgery, and robotics.
DiscoveriesThe Orthopaedic Research Lab is a pioneer in the use of finite element modelling (FEM) for bone implants. Its expertise was acknowledged by the European Research Council by ERC-Advanced Grant on Biomechanical Diagnostic, Pre-Planning and Outcome Tools to improve Musculoskeletal Surgery (BioMechTools). The research on this subject is acknowledged worldwide as pioneering and leading research.
Research within MITeCThe Orthopaedic Research Lab has several studies that are partly done within the MITeC environment. For example, the MITeC operating rooms are used for a study on 3D surgical planning and intra-operative navigation for the removal of bone tumors. This technique will allow better insight in the complete removal of bone tumors in challenging positions, such as the lumbar spine. More complete removal will also result in a smaller change of the tumor recurring.
Another project, focusing on minimal invasive surgical treatment of skeletal metastases, is partly funded by MITeC. The aim is to develop a surgical tool that will allow for the removal, cryotherapy and cementation of skeletal defects. Currently, patients are treated with radiotherapy and analgesics. Thus far, this method shows a partial pain relief with a long onset time. Minimal invasive treatment can possibly improve this.
ProjectsThe Orthopaedic Research Lab received European grants for several projects.
The TLEMsafe project run from 2010 to 2014 (with PhD candidates obtaining their PhD in 2018). Click here for the video "TLEMsafe - patient-specific surgical navigation".
The TLEMsafe project was followed by the ERC-BioMechTools project, which run from May 2013 to April 2018.
The MyLeg project runs from January 2018 to December 2021.
Since 2010, the Orthopeadic Research Lab runs a meniscus project: click here for a video about the project, and click here for more information about it (in Dutch).
External project websites
MITeC Connected operating rooms, for advancing innovation in patient care
MITeC offers unique consulting services and expertise to incorporate newly developed medical technology innovations and accelerate their success rate.read more
Radboudumc Technology Center 3D lab
The focus in the 3D Lab is how we can use 3D technologies to improve care for each individual patient. These new technologies help improve the care and the treatment plan of patients, while taking their specific individual needs and wishes into consideration.read more