News

ScreenPoint Medical raises $28 million for further development Series C funding led by Insight Partners

ScreenPoint Medical has raised $28 million in a Series C financing. ScreenPoint Medical is a spin-off of the Radboudumc.

Next Generation cytogenetics is on its way Does Optical Genome Mapping turn cytogenetics upside down?

Dutch-French research shows that Optical Genome Mapping (OGM) detects abnormalities in chromosomes and DNA very quickly, effectively and accurately.

Human microbiome could shed light on higher morbidity rate in minoritized populations The link between environmental inequities and disease may lie in the gut

A study published in PNAS is the first to explicitly address the gut microbiome as a pathway to understanding how environmental inequities could lead to health disparities.

European research project raises hopes in fight against rare diseases Solve-RD successfully established an innovative approach to jointly re-analyze genomic and phenotypic data from unsolved rare disease patients

For the first time in Europe hundreds of rare disease experts team up to actively share and jointly analyze existing data from unsolved rare disease patients.

Joining forces with patient communities to drive FAIR data

Nawel van Lin created a new animation, which was presented during the event on Duchenne data sharing to spread awareness of the benefits of FAIR.

Detecting more rare diseases through analysis in three dimensions contributed by Radboudumc, BioProdict and Vartion

Martijn Huijnen, will lead an European Regional Development Fund (EFRO) project entitled "Diagnostics-in-3D".

Radboudumc scientists in international list of most cited scientists

The list of the 1 percent most cited scientists of the past ten years contains seventeen scientists who are affiliated with Radboudumc or Radboud University. The list was published by Clarivate Analytics.

FAIR data is necessary but what can it bring you?

As a researcher you are obliged to manage your data following the FAIR principles. But is it only a necessity or does it actually have advantages? The Radboudumc takes you along in a number of these showcases.

Tom Ederveen

Recently awarded with the best publication award, this dedicated researcher loves DNA as much as Salvador Dali does. He lost his childhood in Jurassic Park, but eventually became interested in the art of making data meaningful. Time to get a glimpse of his vision for a sustainable science practice.

Best publication award of 2019 in dermatology awarded to Jos Smits and Tom Ederveen

The Dutch Society for Experimental Dermatology (NVED) awarded the publication in Journal of Investigative Dermatology of Jos Smits and Tom Ederveen.

Software for ranking protein-protein interfaces Released by eScience Center

Li Xue of the CMBI contributed to the development of a software package that ranks and scores protein-protein interfaces (PPIs). This article was published in Software X.

Young Investigator Poster Award at ESHG 2020 for Anouk Verboven

The Best Poster in Basic Research was awarded to Anouk Verboven, PhD student at the Department of Human Genetics and at the CMBI.

Metakids-UMD grant for Purva Kulkarni

The Metakids foundation has awarded 220.575 Euro to support the establishment of a multi-omics biomarker platform within the United for Metabolic Disease (UMD) consortium.

UMCs work together on the FAIRification of patient registries

It has become easier for scientists working with rare diseases to exchange research data. By researchers from Radboudumc and Amsterdam UMC, a rare disease registry codebook has been created. The codebook facilitates data exchange between institutions with different electronic data capture software.

The new front line: big data podcast

What role do big data and technology play in the fight against corona? What data can help save lives? How do you ensure that your personal health data is used safely? Among others, Peter-Bram 't Hoen explains.

MetaDome highly accessed

MetaDome was recently recognized as one of the most accessed articles of 2018-2019 in Human Mutation. The MetaDome was a project developed by Laurens van de Wiel, Christian Gilissen, and Gert Vriend.

Oud-collega Robin van der Lee in Vancouver

Comparison of RNAseq analysis methods published in Genome Biology

Radboud Bioinformatics Xmas event 16 December

The CMBI is organizing the event of the year for all bioinformaticians throughout Radboud University and Radboudumc to give you the opportunity to bring forward the biggest challenges in your research to expert bioinformaticians and pave the way for real solutions.

Towards molecular therapies for Myotonic Dystrophy

ReCognitION, a new 1.3 M€ European project under the leadership of Peter-Bram ‘t Hoen, Baziel van Engelen and Jeffrey Glennon, was kicked-off in Gent.

RIMLS PhD grants awarded to eight RIMLS (j)PI's

Recently, RIMLS held an internal call for Radboudumc junior researcher (PhD) positions. Congratulations for all the awardees and all the best in conducting the research projects.

H2020 grant for a new EATRIS flagship project on personalised medicine

EATRIS obtained funding for a new flagship project for sustainability and personalised medicine: EATRIS-Plus. Alain van Gool, Peter-Bram ‘t Hoen and Ariaan Siezen are co-PI’s and receive approximately 550 k€ from this 5M€ Horizon2020 infrastructure development grant.

Front cover Human Mutation

The MetaDome web server build to interpret genetic variants based on genetic tolerance and homologous protein domains is featured on the Cover of Human Mutation. MetaDome was developed by Laurens van de Wiel, Coos Baakman, Daan Gilissen, Joris Veltman, Gert Vriend and Christian Gilissen,

Successful Summer School by CMBI, TML and Human Genetics

CMBI, TML and Human Genetics organized a successful Summer School on 'Integrative X-omics Analyses Empowering Personalized Healthcare'.

Final scientific pitch competition Radboud Talks

The finalists of the scientific pitch competition Radboud Talks have been selected. On Monday evening 25 March, eight scientists will compete in LUX for the award.

Valentine’s day spectacle at the Radboud Research Rounds

This year’s Valentine’s day in the Radboudumc was focused on the RRR of the Tumors of the Digestive Tract. In the biannual Paper Award session the big prize went to Daniel Garza from the Center for Molecular and Biomolecular Informatics, for his paper on “the environmental metabolome”.

TDT paper award for Daniel Garza

The Nature Microbiology paper by the CMBI researchers Daniel Garza, Martijn Huynen, and Bas Dutilh won the first place in the paper award session of the Tumors of the digestive tract research theme.

Nature Methods paper on GPCR structure determination

The most recent addition to the GPCR database is a web tool to make the design of crystal constructs easier. CMBI Master's student Janne Bibbe was part of this project, and is now co-author of the paper "An online resource for GPCR structure determination and analysis" in Nature Methods.

COPAL reveals remodeling of mitochondrial protein complexes in Barth syndrome

Martijn Huijnen, theme Mitochondrial diseases, and colleagues developed COmplexome Profiling ALignment (COPAL) to systematically asses the effect of Barth syndome on mitochondrial protein complexes. They published their findings in Bioinformatics.

Five RIMLS researchers in top 1 percent by citations

Bas Dutilh, Leo Joosten, Jos van der Meer, Mihai Netea and Henk Stunnenberg made it to this year’s list of highly cited researchers. Researchers in this list are selected for their exceptional research performance and are regarded to have had a major impact on fellow scientists.

Minister pleads for a better use of big data in healthcare

The minister for medical care and sport, Bruno Bruins, sent his recommendation regarding the use of big data in healthcare to the House of Representatives. In order to securely share data, the Personal Health Train project was established. Peter-Bram ‘t Hoen is one of the project leaders.

BBMRI-Omics wins Dutch Data Prize 2018

Stan Gielen (president NWO) handed out the Dutch Data Prize (Nederlandse Data Prijs) to the BBMRI-Omics data collection.

ZonMw grant to promote large scale (re)use of DNA data

Collaborative effort towards enhanced reusability of DNA data facilitates future personalized medicine approaches.

The European Joint co-fund Programme for Rare Diseases (EJP-RD) approved

Radboudumc participates in the European Joint Programme on Rare Diseases (EJP-RD), which was recently approved by the European Commission.

Netherlands X-omics Initiative: Consortium kick off meeting

The Netherlands X-omics Initiative had their consortium kick-off meeting. Consortium members from the Dutch partners involved gathered to get to know each other and to determine the next steps to start up the project.

RTC Bioinformatics Network Event From -omics data to biological knowledge

Last Tuesday, the 8th floor of the RILMS building provided the stage for the Radboud Technology Center for Bioinformatics  event  titled “From -omics data to biological knowledge”.

Predicting metabolites based on bacterial genes

What do the bacteria eat, that live on your skin? Scientists at Radboudumc and Utrecht University have developed a novel computer model to answer this question, revealing that a lot of the food for skin bacteria is derived from beauty and skin care products.

Peter-Bram ‘t Hoen appointed as professor of Bioinformatics and head CMBI

Welcome Peter-Bram, as new head of the Centre for Molecular and Biomolecular Informatics (CMBI).

CMBI researchers develop building blocks and recipes for Computer-Aided Drug Discovery

Following the development of a virtual machine (JCIM), the 3D-e-Chem team now published a series of building blocks and recipes that can support complex computer-aided drug discovery efforts.

Publication in Human Mutation Using homologous relationships of protein domains in the human genome to interpret genetic variation

This publication is part of the PhD project of Laurens van de Wiel and shows how homologous protein domain relations may be used to interpret normal and pathogenic variation at a much finer scale than previously possible.