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Research Departments Center for Molecular and Biomolecular Informatics

Center for Molecular and Biomolecular Informatics

The Center for Molecular and Biomolecular Informatics (CMBI) does research and education, and provides services in bioinformatics and cheminformatics.

Merging of departments

As of February 2023, this department is part of the new Medical BioSciences department.

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Contact Head of the CMBI

prof. dr. Jolanda de Vries
head of department

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Mission & vision

Our mission

Our mission is to add value to personal health data by their translation into integrative knowledge and actionable information.

Our vision 

  • CMBI develops bioinformatics approaches that contribute to the understanding of disease mechanisms, personalized therapies and interventions, and a learning health care system
  • CMBI is committed to the reusability of their data, tools, and services
  • CMBI provides  bioinformatics researchers in Radboudumc with a platform for exchange of knowledge and expertise
  • CMBI contributes to the education of BMW, MLW, and MMD students so that they can apply and understand the principles behind (existing) bioinformatics tools

Radboudumc Technology Center Bioinformatics

The Bioinformatics technology center aims to raise and solve biological questions using the most recent computer technologies and big data solutions.

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Our mission is to provide a basic understanding in Bioinformatic principles. Follow-up courses are available for those who want to gain greater insight in our field. read more


Researchers at the CMBI contribute to several courses at both the Faculty of Science and the Medical Faculty. We provide courses in Structural Bioinformatics, Comparative Genomics, Data Analysis, and programming courses such as Java. We specifically focus on the Molecular Life Science students, Biomedical Sciences students and participants in the master Molecular Mechanisms of Disease, although some of our courses can be chosen by Biology, Chemistry or Medical students as well. 

Our mission is to provide a basic understanding in Bioinformatic principles for bachelor students as this was shown to be beneficial for those who want to pursue a career in Life Sciences. Follow-up courses are available for those who want to gain greater insight in our field. 

For MLS/Biology students it is even possible to follow the B-track by choosing a combination of (master) Bioinformatics courses and internships at Bioinformatics departments. 

Our researchers also teach in special interest courses and summer schools here at the Radboudumc, the Radboud University and elsewhere.


For more information, you can contact dr. Hanka Venselaar, education coordinator at the CMBI.




The CMBI offers a wide range of possibilities for internships. read more


Both bachelor and master students from studies such as Molecular Life Sciences, Biomedical Sciences, Chemistry and MMD are welcome. In general, we are flexible in terms of internship length, type of internship and type of research. 

Below you can find our internship projects:

  • Background

    The Plasmodium falciparum NF135 isolate from South East Asia is oddly resistant to a range of drugs including commonly used laboratory and clinical compounds, and has had unexpected resistance in clinical trials leading to treatment failure in patients. To identify why and look for a potentially new or extreme drug resistant phenotype we must look in detail at the genomic sequence of NF135 in comparison with other closely related strains of NF135 with less resistance to identify mutations, duplications, and/or deletions (also including a negative control well know highly susceptible NF54 strain) that could be linked to drug resistance. This project will start with sequence data from NF135 and the available sequence data from K1 and W2 (W2mef or Dd2) which are South East Asia lines with much lower and very specific drug resistant profiles. If time permits the possibility of inducing these mutations in NF54 highly drug susceptible line will also be investigated.


    Martijn Huynen ( in collaboration with Nick Proellochs (


Diagnostics-in-3D progress update 2021


Update on the EFRO funded project Diagnostics-in-3D.

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Our researchers CMBI

A list of researchers connected to this department. read more

Contact Business manager

Arthur Willemsen
Business manager


Contact Operational manager

Barbara van Kampen
Operational manager

+31 (0)24 361 93 90

Contact Management assistent

Sandra de Leeuw
Management assistent


Research themes