News

Human pDCs attract cytolytic lymphocytes in anti-cancer vaccination

RIMLS researchers Jasper van Beek and Jolanda de Vries, theme Cancer development and immune defense, discovered that pDCs can efficiently recruit cytolytic immune effector cells, a property that could be exploited in anti-cancer vaccines. They have published these findings in Cell Reports.

ZonMw funding for teams of Michiel Vermeulen and Jolanda de Vries

The awarded research projects of RIMLS researchers Michiel Vermeulen, Jolanda de Vries, Gerty Schreibelt and Martijn Verdoes and colleagues will initiate new research lines and collaborations between various research groups.

Niels Stensen Fellowship for Jorieke Weiden

Jorieke Weiden was recently awarded a grant from the Niels Stensen Fellowship. Since the 1960s, the Niels Stensen Fellowship has been awarded annually to outstanding researchers who recently received their PhD to enable them to gain research experience at a top university or institute abroad.

Galectin-9 controls plasma membrane integrity of dendritic cells

Laia Querol Cano, theme Cancer development and immune defense, has discovered how galectin-9, a sugar-binding membrane organiser, governs dendritic cell function by intracellularly modulating actin cytoskeleton. These findings are published in the latest issue of iScience.

New insights into the initiation of T cell responses in the spleen

Carl Figdor and colleagues, theme Cancer development and immune defense, provide insights into the initiation of T cell responses in the spleen and their consequences for T cell differentiation. They have published their results in Proceedings of the National Academy of Sciences USA.

Jubilee lecture and symposium Carl Figdor

For Carl Figdor, theme Cancer development and immune defense, who has been active in the field of tumor immunology for 40 years, a jubilee lecture and symposium will be organised. 

'Radboudpluim' for Jeanette Pots

Jeanette Pots received the 'Radboudpluim' from Paul Smits, for her exceptional services as technician at the department of Tumor Immunology.

New technique boosts preclinical antibody research

Martijn Verdoes, theme Nanomedicine, and Bas van der Schoot, theme Cancer development and immune defense, developed a technique to engineer and produce antibodies quickly, easily and cheaply. The researchers published their results in the open access journal Science Advances.

Publication in Blood on CD37 mutations in lymphoma

Suraya Elfrink, in Annemiek van Spriel's research group Immune cell signaling, theme Cancer development and immune defense, published a manuscript in Blood reporting that tetraspanin CD37 is frequently mutated in patients with diffuse large B cell lymphoma occurring at immune-privileged sites.

A personal touch of Jeroen Creemers

In order to promote interaction amongst colleagues within RIMLS, we have a ‘personal touch’ series setting employees in the spotlight. A light-hearted manner to learn about the colleagues you know and those you don’t. This week: Jeroen Creemers.

Three VIDI grants for RIMLS researchers

Matthijs Jore, Daniele Tauriello and Johannes Textor are each to receive up to 800,000 euros to develop an innovative research theme and to build up their own research group. NWO is awarding the Vidi grant as part of the Innovational Research Incentives Scheme.

ERC Advanced Grants for RIMLS researchers

Carl Figdor and Mihai Netea have each received an ERC Advanced Grant. The amount varies per grant, but is approximately 2.5 million euros. They can use this funding to continue their research for the next five years.

Publication on nanoparticle imaging agent

Mangala Srinivas, theme Nanomedicine, showed in Advanced Functional Materials that nano‐particles (radius 100 nm), are suitable for long‐term in vivo ultrasound in combination with 19F MRI and fluorescence.

A personal touch of Georgina Flórez Grau

In order to promote interaction amongst colleagues within RIMLS, we have a ‘personal touch’ series setting employees in the spotlight. A light-hearted manner to learn about the colleagues you know and those you don’t! This week: Georgina Flórez Grau.

A personal touch of Floris van Dalen

In order to promote interaction amongst colleagues within RIMLS, we have a ‘personal touch’ series setting employees in the spotlight. A light-hearted manner to learn about the colleagues you know and those you don’t! This week: Floris van Dalen.

RIMLS awards festival Twelve winners

In 5 categories RIMLS young researchers received an award and bonus during the New Year's drinks. See all photo's.

Jolanda de Vries on Dutch National TV in 'Dokters van Morgen'

On Tuesday 15 January, presenter Antoinette Hertsenberg, interviewed Jolanda de Vries, theme Cancer development and immune defense, for a program on Dutch National TV, called the 'Dokters van Morgen'.

Mangala Srinivas elected chair of the Young Academy of Europe

The YAE is a pan-European initiative of outstanding young scientists for networking, scientific exchange and science policy.

Rare immune cells kickstart anti-cancer immune response

Florian Wimmers, theme Cancer development and immune defense, and colleagues developed a high-throughput nano lab to shed light on this process. Their findings were published in Nature Communications.

A personal touch of Elke Muntjewerff

In order to promote interaction amongst colleagues within RIMLS, we have a ‘personal touch’ series setting employees in the spotlight. A light-hearted manner to learn about the colleagues you know and those you don’t! This week: Elke Muntjewerff.

A personal touch of Suraya Elfrink

In order to promote interaction amongst colleagues within RIMLS, we have a ‘personal touch’ series setting employees in the spotlight. A light-hearted manner to learn about the colleagues you know and those you don’t! This week: Suraya Elfrink

Tetraspanins protect against renal disease

Annemiek van Spriel, theme Cancer development and immune defense, and Johan van der Vlag, theme Renal disorders, showed in Kidney International that tetraspanin CD37 protects against IgA nephropathy by inhibition of the IL-6 pathway.

A personal touch of Harm Westdorp

In order to promote interaction amongst colleagues within RIMLS, we have a ‘personal touch’ series setting employees in the spotlight. A light-hearted manner to learn about the colleagues you know and those you don’t! This week: Harm Westdorp.

Nanovaccines through adjuvant‐induced tumor antigen assembly

In a recent publication in the journal Small, Liping Qiu in the group of Carl Figdor and Martijn Verdoes turned this disadvantage into an advantage by inducing antigen assembly using immune stimulating adjuvants.

Release of IL-6 from dendritic cells

Publication in ELife by Daniëlle Verboogen, Geert van den Bogaart and colleagues, theme Cancer development and immune defense.

Annemiek van Spriel appointed Professor of Experimental Immunology

We proudly introduce our new professor at the Dept. of Tumor Immunology. Her research focuses on the role of membrane proteins in the development of cancer.

Christine Mohrmann stipendium for Jorieke Weiden and Miriam Haaksma

The Christine Mohrmann stipendium is awarded yearly to 10 promising female PhD candidates from the different faculties of the Radboud University in Nijmegen.

ERA-NET grant on imaging in cardiovascular disease

Subclinical atherosclerosis characterization: Nanoparticle-based molecular and cellular imaging (SCAN).

Jolanda de Vries wins Huibregtsen Prize

For her work on natural dendritic cell vaccines.

Ethylene, an early marker of systemic inflammation in humans A study published in Scientific Reports

This study was recently accepted for publication in Scientific Reports.

Publication in Elife Group Geert van den Bogaart

Measurement of membrane trafficking in dendritic cells by FLIM

Publication in Science Signaling Group of Annemiek van Spriel

Tetraspanin microdomains control localized protein kinase C signaling in B cells

Internal KWF review procedure 2017-2

Radboudumc Medal for Jolanda de Vries

During the New Years 2017 Jolanda de Vries was honored with the “Radboud Medal″.