Computational approaches to advance personalized medicine
Peter Bram 't Hoen's research group develops computational approaches that exploit molecular –omics data in combination with clinical data to better understand disease mechanisms and to advance patient diagnosis and stratification for therapeutic and life style interventions.
Renal electrolyte handling
René Bindels' research group studies the regulation of ion transport processes in kidney and small intestine in health and disease. Current projects involve the molecular mechanisms underlying rare tubulopathies and the regulation of the newly identified calcium, magnesium and sodium transporters.
William Leenders' group performs targeted quantitative next generation sequencing of RNA from surgery-derived cancer tissues in retrospective studies, tries to translate the findings into personalized precision therapy with available cancer treatments, and develops innovative targeted nanomedicines.