News

Large AI project receives over €95 million for ten years of public-private research

The Dutch Research Council (NWO) is to fund two consortia for a period of ten years. Radboudumc participates in the ROBUST consortium, which consists of 17 AI labs, eight of which are dedicated to healthcare. Radboudumc leads five of these eight labs.

New Automated PBMC isolation method introduced in LMI.

The Radboud Biobank (RB) and the laboratory of Medical Immunology (LMI) are making plans to replace the density gradient centrifugation method with a new automated PBMC isolation method, the AutoMACS Pro Separator.

Health-RI, geared up to accelerate

The Dutch cabinet has selected Health-RI's National Growth Fund proposal for a national health data infrastructure. On 5 October, the kick-off will take place during a live meeting in Jaarbeurs Media Plaza in Utrecht.

SUNRISE-CRC sub-biobank

The main purpose of SUNRISE-CRC is to determine whether treatment with a high dose of sunitinib provides a better chance of survival and slows the progression of (colo)rectal cancer (CRC) more than standard treatment with TAS-102.

PRECISE sub-biobank

The aim of the PRECISE biobank is to develop the first, smart multi-modal liquid biopsy test service for the prediction of immune checkpoint inhibitor response in urothelial cancer (UC) patients – the PRECISE IVD.

Lysine Metabolism sub-biobank

Hereditary metabolic disorders form a large group of more than 1,400 rare disorders in which an error in the DNA causes abnormalities in the process in which proteins, fats and carbohydrates are converted into smaller building materials and energy.

Hyperintense sub-biobank

Cerebral small vessel disease (SVD), encompasses a collection of pathologies that affect the smallest blood vessels in the brain.

Duchenne Muscular Dystrophy Parel

Duchenne muscular dystrophy (DMD) is a rare X-linked hereditary disorder (locus Xp21.2) and therefore occurs almost exclusively in boys.

ADOPT sub-biobank

In the multicenter clinical study ADOPT, 280 men with oligo-recurrent prostate cancer from 10 participating hospitals in the Netherlands are randomized to receive standard metastasis-targeted radiotherapy or metastasis-targeted radiotherapy in combination with 6 months of ADT.

Myotonic Dystrophy sub-biobank

Myotonic Dystrophy is an autosomal dominantly inherited multisystem disorder (MD type 1 and MD type 2).

Radboud Biobank Oncology

The Radboud Biobank Oncology stores biomaterial (plasma, serum, cfDNA, tumor tissue) from patients with a proven malignancy or a high suspicion of malignancy, together with data about the patient's disease course.

New start-up Patholyt will bring AI research into pathology diagnostics

Patholyt is on a mission to accelerate the adoption of artificial intelligence in pathology diagnostics and improve the chances of cancer patients worldwide. Patholyt is a spin-off from Radboudumc, a frontrunner in computational pathology research.

Cooperating T cells clear tumor cells more effectively

Live imaging: immune cells attack tumor

Nijmegen literally puts Digital Health on the map Flourishing ecosystem gets its own interactive overview

Digital Health is thriving in the Nijmegen region, where it contributes to better care and health and also creates jobs. To bring developers and end users even closer together, The Economic Board and the Radboudumc are introducing the Interactive Digital Health map.

Next Generation cytogenetics is on its way Does Optical Genome Mapping turn cytogenetics upside down?

Dutch-French research shows that Optical Genome Mapping (OGM) detects abnormalities in chromosomes and DNA very quickly, effectively and accurately.

Vooijs award for Merel van der Stelt

Merel van der Stelt has won the Vooijs Award with her final research project 'Making prosthetic devices' in the 3D lab at the Masanga Hospital in Sierra Leone. This award goes to the most clinically relevant final research project in the Technical Medicine educational programmes in the Netherlands.

First volunteers vaccinated with Radboudumc malaria vaccine

Today a new vaccine against malaria, largely developed in Nijmegen, is being tested for the first time in volunteers at Radboudumc.

Overview of samples in storage

It is possible to request an overview of the samples stored in a sub-biobank when desired.

Magazine celebrating 10 years BBMRI.nl

In the past 10 years, BBMRI.nl has made great progress in fulfilling its mission to maximize the use of biomaterial, images and clinical data for health research.

Growth Fund invests in Health-RI proposal for health data infrastructure

The Dutch Government has decided to honor Health-RI's proposal for a national health data infrastructure.

GENPAD sub-biobank

The GENPAD Biobank is part of the GENPAD study and contains biomaterial and clinical data from patients with peripheral arterial disease.

CORONIS sub-biobank

The CORONIS Biobank will focus on research into the pathophysiology of ischemic stroke after COVID-19 infection.

Vici grant for Michiel Vermeulen Reading the epitranscriptome

Michiel Vermeulen, theme Cancer development and immune defense, has been awarded a Vici grant from the Netherlands Organisation for Scientific Research (NWO), one of the largest personal scientific awards in the Netherlands.

Miljoenen voor kennis- en investeringsconsortium op het gebied van AI

Een kennis- en investeringsconsortium met het Radboudumc heeft acht miljoen euro subsidie gekregen om innovatie op het gebied van Artificial Intelligence (AI) versneld naar de markt te brengen.

Genetische pleister ‘remt’ blindheid in patiënten met Usher syndroom Leidse ProQR bouwt onderzoek Radboudumc verder uit

Het Leidse biotechbedrijf ProQR Therapeutics presenteerde deze week positieve resultaten van een klinische fase I/II studie met het molecuul QR-421a, een molecuul dat in de vroegste fase is ontwikkeld door onderzoekers van het Radboudumc

Current overview of intriguing RNA therapies

In an article in EMBO Molecular Medicine, researchers from Radboudumc, together with European colleagues, provide an up-to-date overview of the (im)possibilities of these intriguing RNA therapies.

Framework for standards and assessment of accessing identifiable patient data for medical scientific research

A Framework for standards and assessment of accessing identifiable patient data for medical scientific research has been developed in the Radboudumc.

Animation Radboud Biobank for patients

The Radboud Biobank has had an animation made to inform Radboudumc visitors about the Radboud Biobank and its purpose.

HEALTH-RI Biobank Community

Biobanks are an indispensable part of the infrastructure for health research. That is why BBMRI.nl, Parelsnoer and Health-RI are joining forces.

RICH sub-biobank

Spontaneous intracerebral hematomas (ICH) are the most deadly form of stroke. The RICH biobank collects biomaterial (DNA, plasma, serum and PAXgene) from patients with spontaneous ICH.

SHM sub-biobank

Stichting HIV Monitoring’s (SHM) mission is to increase knowledge and understanding of all relevant aspects of HIV infection.

REGenG sub-biobank

The Radboud Expertise Center Sex & Gender (REG & G) is responsible for patient care, education, and research regarding gender incongruity / dysphoria.

Review of the Code of Conduct for Health Research

A public review of the full draft Code of Conduct is expected to occur in early 2021.

Assessment of research with material from an existing biobank.

If you want to perform research with material from a biobank and the initiation of this biobank has already been approved by the CMO Radboudumc, you only need to submit an application to the CMO Radboudumc for assessment in certain cases.

Sub-biobank MEMORY

The MEMORY biobank focuses on research into biomarkers for memory impairment and dementia and their validation in clinical cohorts.

Sub-biobank CDG Congenital Disorders of Glycosylation

RYR1 sub-biobank

The RYR1 biobank is part of a study of the neuromuscular and multisystem features of patients with malignant hyperthermia or rhabdomyolysis related to RYR1 (ryanodine receptor type 1) variants.

New colleague

My name is Robbert Croes and I started mid 2020 as a data-scientist at the Radboud Biobank.

ProBCI sub-biobank

There is a pressing need for predictive biomarkers to personalize bladder cancer treatment.

Financial regulation for sub-biobanks

Sub-biobanks are not required to pay up-front for the processing and storage of biomaterials. The effectiveness of this pre-financing agreement however is dependent on adherence to the demands regarding delivery and processing according to the Radboud Biobank standard operating procedures.

Software for ranking protein-protein interfaces Released by eScience Center

Li Xue of the CMBI contributed to the development of a software package that ranks and scores protein-protein interfaces (PPIs). This article was published in Software X.

Biobanking: the power of collecting

Urine, cerebrospinal fluid, blood. Everything is stored in Dutch biobanks. Collecting this takes a lot of time and money. Is it worth that? What does it yield?

Costs for internal researchers in case of request for samples

As of January 1, 2020, internal researchers who request samples from the Radboud Biobank will only be charged for the number of samples received.

New sub-biobanks

The Radboud Biobank has added one new sub-biobank to the collection: HEMLYM.

Otto Boerman in the Dutch radio show "Met het oog op morgen"

Otto Boerman, director of the Animal Research Facility (CDL), was interviewed on NPO radio 1 on studies in laboratory animals for the development of a vaccine against COVID-19.

RTC Bioinformatics open online office hour

Now that everyone is working from home and has a little more time for the data analysis, we can assume that you might have some questions. Check in on Monday 30 March, 11:00 hrs.

Biobank OPMD

In oculopharyngeal muscular dystrophy (OPMD), muscle strength slowly decreases due to a breakdown of muscle cells. The Biobank OPMD contains clinical data and residual biomaterial.

Biobank BVO

The Biobank BVO contains left-over cytological material from the cervical screening program. The ambition of the BVO Biobank is to make this residual material available for scientific research.

BBMRI-NL series on sustainable biobanking

BBMRI-NL has made a series on sustainable biobanking, combining current knowledge from literature, workshops, and focus groups.

Pilot Broad Consent at the Gate

In line with the NFU initiative “Broad Consent at the Gate” (Breed Consent aan de Poort), the Radboud Biobank is currently conducting a feasibility study examining consent procedures for the use of residual material for scientific research.