Research Themes Nanomedicine Homebuilt multicolor 3D super-resolution microscope
In 2015, Cambi initiated the construction of a super-resolution microscope which can now be exploited for the nanoscopic imaging (10-20 nm lateral and 50 nm axial resolution) of many types of fluorescent biological samples to for example study cell-matrix interactions or the plasma membrane at the nanoscale in health and disease. This state-of-the-art setup is more stable, faster, acquires larger fields of view, and contains more powerful lasers compared to expensive commercial alternatives. The software that controls the microscope is flexible and open source allowing its users to customize features according to their needs. This unique homebuilt setup will soon be part of the microscopy infrastructure of the RTC Microscopic Imaging Center and become available to all researchers within the institute.