The following news items are related to the research Neurodevelopmental disorders.
Front cover Human Mutation21 August 2019
The MetaDome web server build to interpret genetic variants based on genetic tolerance and homologous protein domains is featured on the Cover of Human Mutation. MetaDome was developed by Laurens van de Wiel, Coos Baakman, Daan Gilissen, Joris Veltman, Gert Vriend and Christian Gilissen,
How a gene called G9a regulates the energy supply for stress18 March 2019
In order to survive, all organisms must be able to detect (threatening) changes in their environment and respond to them adequately and quickly. However, such stress responses (e.g., escape from a predator or immune response to an infection) are very energy-consuming.
3 DCMN researchers among most cited scientists10 December 2018
Christian Beckmann, Jan Buitelaar and Barbara Franke made it to this year’s list of highly cited researchers. Scientists in this list are selected for their exceptional research performance and are regarded to have had a major impact on fellow scientists.
Researchers have found the first risk genes for ADHD New insight into the biology behind ADHD.28 November 2018
A major international collaboration headed by researchers from the Danish iPSYCH project, the Broad Institute of Harvard and MIT, and the Psychiatric Genomics Consortium has - for the first time - identified genetic variants which increase the risk of ADHD.
Very few similarities between the brains of schizophrenia patients Research at group level says little about the individual patient16 October 2018
Patients with a diagnosis of schizophrenia are a heterogenous group with large differences between individuals. Researchers at the Radboudumc showed that only a negligible number of identical features in the brain occur in more than two percent of patients.
Researchers and industry join forces to unravel and treat autism Public-private project AIMS-2 receives 110 million euros from IMI12 July 2018
In a large public-private project, supported by 110 million euros by the IMI, a large consortium of researchers will search for biomarkers with which people with autism can be divided into clear subgroups.
A low cholesterol level is not a good thing21 June 2018
Research shows that low cholesterol can also be harmful. Researchers from Radboudumc and their Australian and American colleagues discovered a new metabolic defect, producing very low cholesterol levels. This causes brain anomalies, developmental delay, epilepsy and typical facial deformities.
Save the date for Radboud New Frontiers 2018: Betere zorg, netwerkzorg?17 January 2018
After standard care, standardized care, and personalized care, network care will be care 4.0. But how exactly do you do that? Should we create new structures for it or is it just a matter of trust and ability to step back?
Save the date for Radboud New Frontiers 2018: Big data, better healthcare?17 January 2018
How is big data influencing healthcare and healthcare research? How will it help us and what are the limitations? The first day of the 12th edition of the Radboud New Frontiers symposium, on 1 November 2018, will give you all the answers (and raises new questions).
Transmural care to improve participation in sick children23 November 2017
Together with the Amalia Children’s hospital and “Stichting Kind en Ziekenhuis”, Chris Verhaak (Medical Psychology, theme Mitochondrial diseases) received a grant of 450.000 euro grant from “Zorginstituut Nederland” for the project TRANSIT.
Intestinal bacteria can affect ADHD Publication in PLOS ONE25 September 2017
For the very first time, researchers have found a possible link between the activity of certain intestinal bacteria and human brain activity. In people with ADHD, the researchers found more bacteria that influence the reward centres of the brain via dopamine.
Intellectual disabilities caused by protein defect Gene function mutates more often than previously thought1 September 2017
Intellectual disabilities are often caused by a mutation that damages a gene, preventing the associated protein from functioning properly. However, a mutation can also change the function of a gene.
Four Veni grants for young Radboudumc researchers28 July 2017
Four researchers from Radboudumc have been awarded a Veni grant the Netherlands Organisation for Scientific Research (NWO). These grants provide highly promising young scientists with the opportunity to further elaborate their own ideas during a period of three years.