News

Combining targeted radionuclide therapy and immune checkpoint inhibition for cancer treatment

Simone Kleinendorst, Sandra Heskamp and colleagues, theme Rare cancers, published in Clinical Cancer Research about their research on combined radionuclide therapy and immunotherapy for cancer treatment.

New method improves diagnostics of lymphoma

Blanca Scheijen and Patricia Groenen of the Department of Pathology, together with a European consortium, developed a diagnostic method that more clearly distinguishes between inflammation and lymphoma in enlarged lymph nodes.

Million Euros to develop therapy against cancer metastasis in bones

In the PlatiBone project, researchers Sander Leeuwenburgh and Sandra Heskamp will test new drugs that combine diagnostics, chemotherapy and radiation

KWF grant for better selection of individuals and lung nodules in lung cancer screening

The Dutch Cancer Society has awarded the consortium project ‘Multi-source data approach for Personalized Outcome Prediction in lung cancer screening’ with a grant of 1,425,000 Euro. Colin Jacobs will lead the work package on using artificial intelligence for accurate risk estimation of lung nodules.

RIMLS awards call for nominations

RIMLS awards several prizes to stimulate and honor our (young) researchers. Upcoming awards are Supervisor of the Year, Best Master Thesis, Best Publication, Best Image and more. Send your nominations now before 24 November 2021.

Tackling cancer with radioactive particles

Professor Sandra Heskamp receives grant for research into cancer treatment with radioactivity

Miniaturized microfluidic platform for automated epigenetic profiling

Together with Fluidigm, a US-based company focusing on microfluidics, the team of Hendrik Marks publishes in Genome Research the development of a powerful plug and play ChIP-seq platform for minute amount of cells, such as embryonic specimens or small biopsies.

Image recognition for population-based lung cancer screening An interview with Bram van Ginneken

Being able to automatically recognize lung tumors on CT scans: professor of functional image analysis Bram van Ginneken developed software within his Vici project that is now used worldwide. The resulting cost savings bring the introduction of a population-based lung cancer screening closer.

Increase radio- and immunotherapy efficacy by targeting hypoxia

In a paper recently accepted by Clinical Cancer Research, Daan Boreel, together with Paul Span, Sandra Heskamp, Gosse Adema and Jan Bussink, reviews the therapeutic potential of decreasing the lack of oxygen (hypoxia) often found in solid tumors.

Radiation boost lowers risk of prostate cancer recurrence

An additional external-beam radiation dose delivered directly to the tumor can benefit the prospects of men with non-metastatic prostate cancer, without causing additional side effects. The risk of relapse within five years for these men is smaller than for men who did not receive this boost.

RIMLS online award ceremony proudly presenting the winners

In this special webinar of the RIMLS New Year Celebration, scientific director René Bindels reviewed 2020 and looked forward to 2021. But more importantly a number of researchers received prizes in the traditional RIMLS awards ceremony. 

Erik van der Heijden received The Distinguished WABIP Regent Award

The 21st World Conference on Bronchoscopy and Intervention Pulmonology (WCBIP) is currently taking place in Shanghai. This is organized by the WABIP. Erik van der Heijden, member of the scientific organizing committee, received the prize ‘The Distinguished WABIP Regent Award'.

Tumor cells stimulate lipid biosynthesis in macrophages

RIMLS researchers wrote in the Journal for ImmunoTherapy of Cancer that improved lipid biosynthesis in human tumor-induced macrophages contributes to their protumoral characteristics.

650,000 Euro funding for research into the phasing out of medication for leukaemia patients

With a 650,000 euro funding from ZonMw, researchers from the Haematology and Pharmacy departments can develop a medication phasing out strategy for patients with chronic myeloid leukaemia. This strategy will be tested in practice.

Improved method for detecting lung cancer

Radboudumc researchers are the only ones in the Netherlands using a new method to make better lung cancer diagnoses earlier stage. Erik van der Heijden and Roel Verhoeven shows that the use of flexible imaging equipment via the natural respiratory tract contributes to a more accurate diagnosis.

Optimizing workup in head and neck cancer (HNC)

In the journal Cancer RIHS researcher Henrieke Schutte described the outcomes after the implementation of a fast-track multidisciplinary integrated HNC care program: time-to-treatment was significantly reduced and survival and patient satisfaction increased significantly without increasing costs.

Strain elastography predicts lung cancer metastases

The first multicenter study by researchers Roel Verhoeven and Erik van der Heijden, in which the added predictive value of elastography by means of endobronchial ultrasound of mediastinal lymph nodes in patients with lung cancer was systematically investigated.

Evaluation of an AI system for detection of COVID-19 on Chest X-Ray images

In the journal Radiology researchers from Radboudumc, Bernhoven Hospital and Jeroen Bosch Hospital described how an artificial intelligence system (CAD4COVID-XRay) can identify characteristics of COVID-19 on chest x-rays with performance comparable to six independent radiologists.

Guiding the surgeon real-time tumor visualization during surgery

Incomplete excision of tumor tissue negatively affects the prognosis of the patient. RIHS researcher Mark Rijpkema and colleagues are working on the development of new dual-labeled tracers and currently are implementing this into the clinic.

Cognitive behavioral therapy reduces severe fatigue in patients with advanced cancer during treatment

In Annals of Oncology, RIHS researchers Hanneke Poort, Marlies Peters, Winette van der Graaf, Ria Nijhuis-van der Sanden and colleagues showed significant effects of cognitive behavioral therapy on fatigue in patients with advanced cancer during treatment with palliative intent.

RIMLS PhD retreat registration is open

Yearly, RIMLS PhD candidates gather for the two-day PhD Retreat. Apart from the science, this event is highly valued for the opportunity to meet and get to know fellow PhD candidates during the social activities. Early bird registration and abstract submission deadline: 4 March 2020.

Is Google's lung cancer AI ready for implementation?

In Nature Reviews Clinical Oncology, Colin Jacobs and Bram van Ginneken discussed the recent paper by Google AI in Nature Medicine on deep learning models for automatic detection of lung cancer from computed tomography.

Theme Rare cancers paper award for Sven van den Bosch

The Radiother Oncology paper by researcher Sven van den Bosch and colleagues, won the first place in the paper award session of the theme Rare cancers. The paper competed with 4 other recent publications produced by radboudumc research groups.

Awarded KWF grants for Radboudumc researchers

KWF is investing 2.7 million euros in five different studies at Radboudumc. The awards are part of the new round of funding by DCS, in which over 34 million euros will be granted to Dutch cancer research. We congratulate our researchers with this funding and wish them success with their great work.

Exploration meeting Academic Alliance on Oncology

Within the Academic Alliance, the Maastricht UMC+ and Radboudumc are already working together in several areas. And this is happening in more and more fields. On 27 November researchers from both umc's met during the fourth Exploration meeting, this time with the theme: Oncology.

RIMLS awards call for nominations

RIMLS awards several prizes to stimulate and honor our (young) researchers. Please find here an overview of the upcoming awards. Deadline 12 December 2019.

X² Ambition Award for Sandra Heskamp

This award is intended for 'coming women’: young, ambitious women at a stage of their careers where they make important career choices. This prize is especially for women who show exemplary behaviour within the organization where they work, but also outside their organization.

A personal touch of Maroeska te Loo

In order to promote interaction amongst colleagues within RIMLS, we have a ‘personal touch’ series setting employees in the spotlight. A light-hearted manner to learn about the colleagues you know and those you don’t. This week: Maroeska te Loo.

KWF Roadshow 11 November 2019

In which way(s) can KWF provide optimal support to oncological research and care? How can we maximize impact on our investments? These questions are pivotal in Ambition 2030: the vision that KWF developed in close cooperation with stakeholders in the oncological field.

RIMLS 25 years jubilee festival The Future is Yesterday

Together with more than 250 colleagues and alumni we celebrated 25 years of research into the molecular mechanisms of disease. During this exciting and informal event, we not only took a trip down memory lane, but also looked ahead to the next 25 years and beyond…...

Drug-induced interstitial lung disease in advanced breast cancer patients receiving everolimus

In Targeted Oncology, Annelieke Willemsen, Carla van Herpen and colleagues, showed that pulmonary function test with diffusion capacity of the lungs for carbon monoxide and serum biomarkers can be of aid to differentiate everolimus-related interstitial lung disease from other respiratory problems.

Bart Kiemeney finishes 1st in the Tour and raises thousands of euros

With over €47,000 on the counter, Kiemeney can see the Tour de France as a great success.

Ivan Zhovannik receives best presenter award at MISP

Ivan Zhovannik was awarded the best presenter award at the MISP 2019 (Medical Imaging Symposium for PhD candidates) held in Groningen.

Experiences with molecular tumor boards

In British Journal of Cancer Annelieke Willemsen, Carla van Herpen and colleagues showed that MTBs may have an important impact on patient care, but challenges remain for the accessibility for cancer patients.

Internal KWF review procedure 2020

In agreement with the existing policy the research board and Radboud Center for Oncology have decided to continue with the mandatory internal review procedure for KWF grant applications.

Varian award for Frank Dankers

Frank Dankers and Timo Deist (Maastricht University) were honored with the Varian award 2019 during ESTRO 2019.

Prophylactic antibiotics reduce hospitalisations and cost in head and neck cancer patients

In European journal of cancer Janneke Ham and colleagues showed that prophylactic antibiotics in locally advanced head and neck cancer patients treated with chemoradiotherapy did not reduce the incidence of (aspiration) pneumonias, but did reduce hospitalisations and tended to be cost-effective.

Internal KWF review procedure 2019

In agreement with the existing policy the research board and Radboudumc Center for Oncology have decided to continue with the mandatory internal review procedure for KWF grant applications.

Sarah Verhoeff wins audience award Radboud Talks Jury chose neuroscientist as overall winner

The winner of the fifth edition of scientific pitch competition Radboud Talks is Suhas Vijayakumar, PhD candidate at the Faculty of Social Sciences and the Donders Institute. Research physician Sarah Verhoeff, Radboud Institute for Health Sciences, won the audience award.

Call for RIMLS Junior Researcher 2020

In 2020 funding will be made available for 8 RIMLS Junior Researcher projects. The call for these PhD grants is now open.

Making pregnancy ultrasound available in developing countries

Many pregnant women in developing countries do not receive an ultrasound examination. As a result, pregnancy risks often go unnoticed, which contributes to the high maternal mortality rates in these countries.

RIMLS awards festival Twelve winners

In 5 categories RIMLS young researchers received an award and bonus during the New Year's drinks. See all photo's.

Internal KWF review procedure 2019

In agreement with the existing policy the research board and Radboud Center for Oncology have decided to continue with the mandatory internal review procedure for KWF grant applications.

Awarded KWF grants for Radboudumc researchers

The Dutch Cancer Society (KWF) has awarded 8 grants to Radboudumc researchers. We congratulate them with this funding and wish them success with their great work.

Metal surgical implants can activate drugs

Marja Bulte-ter Meer and Leo Schultze Kool discovered that the iron in metal surgical implants can activate drugs such as antibiotics, thus enabling targeted therapy.

European Reference Networks illustrative video

Watch here a moving video about the ERN for rare epilepsies which explains what the ERNs do.

Super surgeons together with the RoboSculpt

One of the first autonomous surgical robotics – the RoboSculpt – has been tested pre-clinically on cadavers last week for the first time in our Radboudumc in collaboration with Eindhoven Medical Robotics (EMR).

Report of the 12th New Frontiers symposium Big data, better healthcare? - 1 November 2018

Examples from the application of deep learning to image reading in pathology and radiology and the application of network medicine to monitor infectious disease outbreaks or collective mood states using twitter data showed the huge potential of big data approaches for building better healthcare.

Report of the 12th New Frontiers symposium Better care, network care? - 2 November 2018

No easy answers at this symposium last Friday, only challenges that can be overcome if we succeed in 5 things. First and most radically, put patients in the center of healthcare. Second, start with assessing what the local population needs and not what local professionals have to offer.

Public evening 'Dag Dokter'