Vacancies 93721-Data-scientist-in-translational-glycoproteomics

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About the vacancy

  • 36 hours per week
  • Temporary
  • 2 years with possible extension for another year
  • Scale 10: min € 2911 - max € 4615 gross per month for full-time employment (excluding holiday pay and year-end bonus)

Job description

We are looking for a highly motivated and enthusiastic data scientist who will develop clinically compliant parallel-computing solutions based on existing Bruker PaSER technology. Will you join our team?

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Job description

We are looking for a highly motivated and enthusiastic data scientist who will develop clinically compliant parallel-computing solutions based on existing Bruker PaSER technology. Will you join our team?

In this project we aim to develop GPU-powered parallel computing solutions for real-time data processing, analysis and acquisition parameter adjustment to enable the use of four dimensional (glyco)proteomics data in routine patient care.
 
You will actively interact with Translational Metabolic Laboratory (TML) and Bruker scientists to investigate and apply the potential advantages of collisional cross section information for (glyco)peptide analysis in complex patient samples. Acquired knowledge will be included for the implementation of real-time (glyco)peptide data processing and analysis software to enable on-the-fly adjustment of data acquisition parameters next to ready-when-run results generation capabilities to resolve the current data processing bottlenecks in functional Omics.
 
The position is formally housed within the (glyco)proteomics team of TML where technology innovations by the post-doc will be directly utilized to advance patient care. As this position is at the heart of our TML-Bruker joint Center of Excellence in Translational Omics, regular international project meetings will be held with project members. You will have direct access to knowledge and support from application and R&D experts of both partners during this project.

Tasks and responsibilities:

  • Research the added value of collision cross section data for (glyco)peptide analysis in combination with tandem mass spectrometry.
  • Develop and implement clinically-compliant real-time data processing and analysis solutions for (glyco)proteomics based diagnostics.
  • You are involved in pre-development and research activities with external collaborators at Bruker and act as a link between the clinical research and software development teams.


Profile

We are looking for a candidate with: Academic degree (PhD) in bioinformatics or data sciences, with demonstrated ability in programming. Affinity and prefered expertise with mass spectrometry-based Omics data processing and analytics. Excellent oral and written communication skills. Capacity to...

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Profile

We are looking for a candidate with:

  • Academic degree (PhD) in bioinformatics or data sciences, with demonstrated ability in programming.
  • Affinity and prefered expertise with mass spectrometry-based Omics data processing and analytics.
  • Excellent oral and written communication skills.
  • Capacity to communicate high-level expert knowledge at different levels with team members that are active in different scientific fields.
  • Proactive and enthusiastic.


Terms of employment

Upon commencement of employment we require a certificate of conduct (Verklaring Omtrent het Gedrag, VOG) and there will be, depending on the type of job, a screening based on the provided cv. Radboud university medical center’s HR Department will apply for this certificate on your behalf.

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Terms of employment

Upon commencement of employment we require a certificate of conduct (Verklaring Omtrent het Gedrag, VOG) and there will be, depending on the type of job, a screening based on the provided cv. Radboud university medical center’s HR Department will apply for this certificate on your behalf.

Read more about the Radboudumc employment conditions and what our International Office can do for you when moving to the Netherlands.


Department

The data scientist will be working on a joint collaborative project between Radboud University Medical Center and Bruker Daltonics and will be physically based in the Translational Metabolic Laboratory (TML) of the Radboudumc.

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Department

The data scientist will be working on a joint collaborative project between Radboud University Medical Center and Bruker Daltonics and will be physically based in the Translational Metabolic Laboratory (TML) of the Radboudumc.
 
TML is an ambitious mixed function laboratory with translational research and diagnostics for patient care. We harbor a range of top scientists in the areas of inherited metabolic disorders, mitochondrial disease, glycosylation disorders and more. Translational functional Omics technologies are applied at TML to acquire insights in disease mechanisms and develop novel personalized diagnostics. TML houses a broad range of mass spectrometry equipment including latest generation trapped ion mobility spectrometry – quadrupole time-of-flight tandem mass spectrometry instruments (timsTOF Pro) connected online to GPU-powered real-time data processing hardware (PaSER) and offline cloud-based computing infrastructure (Digital Research Environment). We are a joint Bruker Center of Excellence in Translational Omics and coordinate the Radboud Technology Center Mass Spectrometry and several large national and European projects including the Netherlands X-omics Initiative. 
 
Bruker is enabling scientists to make breakthrough discoveries and develop new applications that improve the quality of human life. Bruker’s high-performance scientific instruments and high-value analytical and diagnostic solutions enable scientists to explore life and materials at molecular, cellular and microscopic levels. In close cooperation with our customers, Bruker is enabling innovation, improved productivity and customer success in life science molecular research, in applied and pharma applications, in microscopy and nanoanalysis, and in industrial applications, as well as in cell biology, preclinical imaging, clinical phenomics and proteomics research and clinical microbiology.

Radboudumc
Radboudumc in Nijmegen strives to be a leading developer of sustainable, innovative and affordable healthcare to improve the health and wellbeing of people and society in the Netherlands and beyond. This is the core of our mission: To have a significant impact on healthcare. To get a better picture of what this entails, check out our strategy.

Read more about what it means to work at Radboudumc and what our people have to say about it.


Contact

All additional information about the vacancy can be obtained from dr. Hans Wessels , proteomics scientist, +31 (0)24 361 69 33, or professor dr. Alain van Gool , laboratory head TML. Use the Apply button to submit your application.

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Contact

All additional information about the vacancy can be obtained from dr. Hans Wessels, proteomics scientist, +31 (0)24 361 69 33, or professor dr. Alain van Gool, laboratory head TML. Use the Apply button to submit your application.

Applicants should send a letter of intent outlining their specific interest in the position, overall related qualifications, experience and career goals, a curriculum vitae and details of professional references.

Please apply before 8 March 2021.
Recruitment agencies are asked not to respond to this job posting.

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