18 April 2018

Dead should be assigned the value 0 in economic models combining survival and quality of life, such as the Quality Adjusted Life Years (QALY) model. This is a result found by researchers Bram Roudijk, Rogier Donders and Peep Stalmeier of the Department for Health Evidence and was published in Medical Decision Making on April 9th , 2018.

The considerations for setting dead at zero
The main reason for setting dead at zero is that in multiplicative models, there should be a health state for which one is indifferent to the duration of that health state. Only dead is a candidate to be this health state.

Effects on decision making
The position of dead needs to be carefully established, as it determines the relative importance of life-improving and life-saving treatments in the allocation of resources in health care.

Publication
Setting Dead at Zero: Applying Scale Properties to the QALY Model
Bram Roudijk, A. Rogier T. Donders, Peep F.M. Stalmeier

This research was conducted within the theme Healthcare improvement science.

Related news items


Large AI project receives over €95 million for ten years of public-private research

23 September 2021

Radboud university medical center (Radboudumc) participates in the ROBUST consortium, which consists of 17 AI labs, eight of which are dedicated to healthcare. Radboud university medical center leads five of these eight labs.

read more

Reading ADP-ribosylation signaling using chemical biology and interaction proteomics published in Molecular Cell

22 September 2021

Kasia Kliza and Michiel Vermeulen worked on a project to synthesize biotinylated ADPr-based probes that can identify ADPr readers and determine their specificity for mono- and polyADPr. They published this in Molecular Cell.

read more

Systematic analysis of short tandem repeats in 38,095 exomes provides an additional diagnostic yield

22 September 2021

Christian Gilissen and colleagues published in Genetics in Medicine about their work guiding the application of short tandem repeat analysis in clinical exome sequencing.

read more

TropIQ seeks new mosquito repellents

21 September 2021

TropIQ Health Sciences, a Radboudumc spin-off, has received a 1.3 million USD grant from the Bill & Melinda Gates Foundation to track down new mosquito repellents.

read more

New start-up Patholyt will bring AI research into pathology diagnostics

21 September 2021

Patholyt is on a mission to accelerate the adoption of artificial intelligence in pathology diagnostics and improve the chances of cancer patients worldwide. Patholyt is a spin-off from Radboudumc, a frontrunner in computational pathology research.

read more

Treatment of most common skin cancer can sometimes wait

20 September 2021

Not treating but keeping an eye on the cancer is also an option

read more