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Research Research groups

Overview of research groups within Radboudumc. You can filter the list with regard to keywords, research institutes, research themes and research departments.

Results (104)

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Bacteriology

Heiman Wertheim's research group is primarily focused on the diagnostics of bacterial infections and antibiotic resistance.

Behavioural neurogenetics

Judith Homberg's research group focuses on genetic and environmental factors that influence brain development and behavioural traits. Interactions between these factors may lead to maladaptive emotional responses as seen in stress-related disorders and addiction.

Biostatistics

Kit Roes's research group aims to continuously improve the quality of medical research, by applying, teaching and developing statistical methods and statistical thinking, aiming for broad use by researchers.

Blindness genetics

Frans Cremers's research group aims to identify the remaining causative retinal dystrophy genes and genetic defects underlying retinal dystrophy in the Netherlands before 2020.

Bone biochemistry

Nico Sommerdijk’s group focuses on the mechanisms of bone biomineralization in both physiological and pathological situations.

Bridging the gap between science and practice for ADHD

Nanda Lambregts-Rommelse's research group is bridging the gap between science and practice for attention-deficit/hyperactivity disorder (ADHD).

Cancer epidemiology

Bart Kiemeney's research group learns as much as possible about cancer with the aim of reducing the burden of this disease. The emphasis lies on the detection of urological tumours and their genetic causes.

Cancer screening and follow-up

Mireille Broeders's research (sub)group looks at whether there’s value to be gained in targeting the screening or follow-up policy to a person’s level of risk, by collecting information on risk factors from screening participants and patients.

Cardiovascular physiology and exercise

Dick Thijssen's research group focuses on the field of cardiovascular physiology and physical (in)activity. His work strongly focuses on understanding the impact of exercise training and physical activity on reducing the risk of developing cardiovascular and metabolic diseases.

Cerebral circulation and cognition in aging humans

Jurgen Claassen's research group uses various techniques to measure cerebral perfusion, cerebral autoregulation and cognitive activation. These physiological mechanisms play an important role in Alzheimer’s disease, hypertension, and cognitive aging.

Cerebral circulation and cognition: Translational neurosciene

Amanda Kiliaan’s research group uses a multidisciplinary approach to study the link between (cerebro)vascular disorders and neurodegeneration. Within this group, neuroimaging is an important tool to study aspects of cerebral hemodynamics (e.g. cerebral blood flow/volume, vasoreactivity).

Cerebral perfusion in neurosurgery

Jurgen Fütterer's and Mark ter Laan's research group explores the feasibility and diagnostic accuracy of cerebral perfusion imaging in neurosurgery. We compare several techniques, and develop new applications for cerebral perfusion imaging in the Hybrid-OR.

Chemical immunology

Carl Figdor's research group studies chemical biology with a focus on the targeting of Dendritic Cells and a focus on developing synthetic Dendritic Cells to directly activate T cells.

Clinical genetics and psychopathology

Tjitske Kleefstra's research group aims to improve care and management of rare genetic neurodevelopmental disorders (NDs) by constructing a concept of personalized healthcare.

Clinical neuroscience in psychiatry

Indira Tendolkar's group focuses the intersection between clinical psychiatry and cognitive neuroscience with a focus on declarative memory. We investigate the adapatation of emotional and neutral memory processes depending on genetic and environmental variablity including somatic challenges.

Clinical pharmacology

Nielka van Erp's research group aims to optimize anticancer treatment in oncology patients by recognizing and addressing interindividual differences and by developing approaches to keep the drugs available for all patients suffering from cancer.

Clinical pharmacology - special populations

Saskia de Wildt's research group uses innovative methods including microdosing and microtracer technology, and physiology-based and population pharmacokinetic modeling, to contribute to a better understanding of the impact of age, disease and genetics on drug disposition in children.

Cognitive and affective neuroscience

Erno Hermans's research group investigates how neurochemicals affect diverse cognitive functions, such as vigilance, executive function, and memory. Moreover, they study how stressful experiences alter the intrinsic neural dynamics in the brain and how such processes contribute to memory.

Cognitive neuroscience of memory and emotion

Guillén Fernández research group aims to gain insights into the declarative memory system, a network of brain structures that enables us to remember events and facts.

Comparative genomics

Martijn Huijnen's research group exploits the wealth of ‘omics data to predict the function of proteins and their involvement in protein complexes and pathways. It thereby specifically focuses on the molecular systems that are of biomedical relevance.

Computational approaches to advance personalized medicine

Peter-Bram 't Hoen's research group develops computational approaches that exploit molecular -omics data in combination with clinical data to better understand disease mechanisms and to advance patient diagnosis and stratification for therapeutic and life style interventions.

Computational pathology group

Jeroen van der Laak's research group develops, validates and deploys novel medical image analysis methods based on deep learning technology and focusing on computer-aided diagnosis.

Dendritic cell vaccination

Jolanda de Vries's research group focuses on dendritic cell vaccination. Dendritic Cell (DC) therapy represents a promising immunotherapeutic approach for the treatment of cancer.

Developmental neuropsychiatry

Jan Buitelaar's research is aimed at a better understanding of neuropsychiatric disorders, such as ADHD, autism, dyslexia and aggression-related disorders, at all levels.

Elderly care medicine

Raymond Koopmans's research group focusses on research on people with dementia or neurological disorders.

Engineered proteins for drug delivery

Wouter Verdurmen’s research group focuses on designing and investigating engineered proteins that overcome delivery barriers, employing synthetic binding proteins for target recognition. Various (super-resolution) microscopy techniques as well as microfluidic tumor-on-a-chip approaches are used.

Establishing physiological biomarkers of perioperative stress

Jurgen Fütterer's group conducts imaging and cognitive research at the intersection between clinical psychiatry and cognitive neuroscience with a focus forms of declarative memory that also play a role in development and maintenance of stress-related mental disorders.

Evidence based surgery

Maroeska Rovers's research (sub)group investigates which surgical techniques are being used and whether or not they are necessary.

Exercise oncology

Laurien Buffart’s research group focuses on the role of exercise in patients with cancer. The multidisciplinary work focuses on the effects and underlying mechanisms of exercise on quality of life and clinical outcome.

Exercise physiology

Thijs Eijsvogels’s research group studies the acute and long-term effects of exercise on health. Current projects involve cardiac imaging following lifelong exercise training, optimizing cardiac rehab, assessing thermoregulatory responses in elite athletes and development of cooling strategies.

Experimental virology

Ronald van Rij's group studies virus-host interactions in both mosquito vector and mammalian host. By doing so, we hope to gain insights into arbovirus transmission and contribute to the development of novel antiviral therapy.

Genetic epidemiology of brain traits and neuropsychiatric disorders

Alejandro Arias Vasquez's goal is to find genes involved in the variation of brain traits as well as for genes involved in the risk of complex neuropsychiatric diseases.

Genetic therapy for inherited retinal disease

Rob Collin's research group aimes at the development of new preclinical therapeutic strategies for selected genetic subtypes of inherited retinal dystrophy, by applying different approaches and using various cellular and animal models.

Genetics of brain function and (psychiatric) malfunction

Barbara Franke's works on the identification of risk genes for disease; in addition to using the classic clinical phenotypes they make use of intermediate phenotypes.

Genetics of multifactorial eye diseases

Anneke den Hollander's research group aims to understand the molecular disease mechanisms of common forms of vision loss, to determine which molecular factors can influence response to therapy, and to stratify patients for the most optimal therapy based on their molecular profile.

Genome bioinformatics

Christian Gilissen's group develops and applies bioinformatics methods to gain insight into the causes and mechanisms of genetic disorders such as intellectual disability.

Genomic profiling in intellectual disability

Bert de Vries's research aims to phenotype patients with intellectual disability to identify genetic mutations and unravel genetic networks underlying intellectual disability.

Genomic technologies & immuno-genomics

Alexander Hoischen's research group focuses on the application of latest genomic technologies to understand human disease. A particular emphasis is put in the understanding of genetic defects that explain immune diseases, in particular primary immunodeficiencies.

Global health priorities

Rob Baltussen's research (sub)group supports decision-makers in countries around the world in setting legitimate priorities for universal health coverage.

Glycosylation Disorders in Neurology

Dirk Lefeber's research group aims to understand the mechanisms of protein- and tissue-specific glycosylation abnormalities in human disease with a focus on neurodegenerative and neuromuscular disease.

Health technology assessment

Gert Jan van der Wilt's research group conducts research into the effectiveness, safety, efficiency and social acceptability of medical technology.

HTA business

Maroeska Rovers's research (sub)group aims to guide new medical technology innovations by facilitating partnerships between the scientific community, medical technology business partners and policy makers.

Human papillomaviruses (HPV)

Willem Melchers's research aims to improve the nationwide cervical cancer screening, with the possibility of using self sampling. Important herein is research on the use of new triage methods for hrHPV positive women, by using HPV genotyping or molecular biomarkers.

Immune cell signaling

Annemiek van Spriel's research group aims to understand how immune cells physically organize and compartmentalize signaling molecules into efficient, regulated membrane-proximal signaling complexes.

Intellectual disability & health

Geraline Leusink's research group has the mission to improve the health and healthcare for people with ID by integrating research, education and patient care.

Intracerebral haemorrhage and stroke

Karin Klijn's research group focuses on causes and consequence of intracerebral haemorrhage and haemodynamic stroke.

Macular degeneration and ophthalmo­genetics

Carel Hoyng's research group specializes in studying the genetics of retinal disorders. The two main research activities are age-related macular degeneration , a research program which has been started to develop better visual rehabilitation, and Ophthalmogenetics.

Magnesium in health and disease

Jeroen de Baaij's research group examines the role of magnesium in health and disease. Our mission is to decipher the pathophysiological mechanisms of magnesoium-wasting tubulopathies by development of novel disease models and advanced methods to measure magnesium transport.

Malaria research

Teun Bousema's, Benjamin Mordmüller's and Taco Kooij's research group focuses on the clinical development of plasmodium falciparum vaccines for control and elimination of malaria.

Meaningful healthcare

Yvonne Engels's research group focuses on optimizing the quality of life of patients, including existential, physical, social and psychological needs.