Research groups - Radboudumc

Behavioural neurogenetics

Judith Homberg's research group focuses on genetic and environmental factors that influence brain development and behavioural traits. Interactions between these factors may lead to maladaptive emotional responses as seen in stress-related disorders and addiction.

Biostatistics

Kit Roes's research group aims to continuously improve the quality of medical research, by applying, teaching and developing statistical methods and statistical thinking, aiming for broad use by researchers.

Blindness genetics

Frans Cremers's research group aims to identify the remaining causative retinal dystrophy genes and genetic defects underlying retinal dystrophy in the Netherlands before 2020.

Bone biochemistry

Nico Sommerdijk’s group focuses on the mechanisms of bone biomineralization in both physiological and pathological situations.

Cancer epidemiology

Bart Kiemeney's research group learns as much as possible about cancer with the aim of reducing the burden of this disease. The emphasis lies on the detection of urological tumours and their genetic causes.

Cancer screening and follow-up

Mireille Broeders's research (sub)group looks at whether there’s value to be gained in targeting the screening or follow-up policy to a person’s level of risk, by collecting information on risk factors from screening participants and patients.

Cardiovascular physiology and exercise

Dick Thijssen's research group focuses on the field of cardiovascular physiology and physical (in)activity. His work strongly focuses on understanding the impact of exercise training and physical activity on reducing the risk of developing cardiovascular and metabolic diseases.

Cerebral circulation and cognition in aging humans

Jurgen Claassen's research group uses various techniques to measure cerebral perfusion, cerebral autoregulation and cognitive activation. These physiological mechanisms play an important role in Alzheimer’s disease, hypertension, and cognitive aging.

Cerebral perfusion in neurosurgery

Jurgen Fütterer's and Mark ter Laan's research group explores the feasibility and diagnostic accuracy of cerebral perfusion imaging in neurosurgery. We compare several techniques, and develop new applications for cerebral perfusion imaging in the Hybrid-OR.

Chemical immunology

Carl Figdor's research group studies chemical biology with a focus on the targeting of Dendritic Cells and a focus on developing synthetic Dendritic Cells to directly activate T cells.

Clinical neuroscience in psychiatry

Indira Tendolkar's group focuses the intersection between clinical psychiatry and cognitive neuroscience with a focus on declarative memory. We investigate the adapatation of emotional and neutral memory processes depending on genetic and environmental variablity including somatic challenges.

Clinical pharmacology

Nielka van Erp's research group aims to optimize anticancer treatment in oncology patients by recognizing and addressing interindividual differences and by developing approaches to keep the drugs available for all patients suffering from cancer.

Clinical pharmacology - special populations

Saskia de Wildt's research group uses innovative methods including microdosing and microtracer technology, and physiology-based and population pharmacokinetic modeling, to contribute to a better understanding of the impact of age, disease and genetics on drug disposition in children.

Cognitive and affective neuroscience

Erno Hermans's research group investigates how neurochemicals affect diverse cognitive functions, such as vigilance, executive function, and memory. Moreover, they study how stressful experiences alter the intrinsic neural dynamics in the brain and how such processes contribute to memory.

Cognitive neuroscience of memory and emotion

Guillén Fernández research group aims to gain insights into the declarative memory system, a network of brain structures that enables us to remember events and facts.

Comparative genomics

Martijn Huijnen's research group exploits the wealth of ‘omics data to predict the function of proteins and their involvement in protein complexes and pathways. It thereby specifically focuses on the molecular systems that are of biomedical relevance.

Computational approaches to advance personalized medicine

Peter-Bram 't Hoen's research group develops computational approaches that exploit molecular -omics data in combination with clinical data to better understand disease mechanisms and to advance patient diagnosis and stratification for therapeutic and life style interventions.

Developmental neuropsychiatry

Jan Buitelaar's research is aimed at a better understanding of neuropsychiatric disorders, such as ADHD, autism, dyslexia and aggression-related disorders, at all levels.

Establishing physiological biomarkers of perioperative stress

Jurgen Fütterer's group conducts imaging and cognitive research at the intersection between clinical psychiatry and cognitive neuroscience with a focus forms of declarative memory that also play a role in development and maintenance of stress-related mental disorders.

Evidence based surgery

Maroeska Rovers's research (sub)group investigates which surgical techniques are being used and whether or not they are necessary.

Exercise physiology

Thijs Eijsvogels’s research group studies the acute and long-term effects of exercise on health. Current projects involve cardiac imaging following lifelong exercise training, optimizing cardiac rehab, assessing thermoregulatory responses in elite athletes and development of cooling strategies.

Genetic epidemiology of brain traits and neuropsychiatric disorders

Alejandro Arias Vasquez's goal is to find genes involved in the variation of brain traits as well as for genes involved in the risk of complex neuropsychiatric diseases.

Genetic therapy for inherited retinal disease

Rob Collin's research group aimes at the development of new preclinical therapeutic strategies for selected genetic subtypes of inherited retinal dystrophy, by applying different approaches and using various cellular and animal models.

Genetics of brain function and (psychiatric) malfunction

Barbara Franke's works on the identification of risk genes for disease; in addition to using the classic clinical phenotypes they make use of intermediate phenotypes.

Genetics of multifactorial eye diseases

Anneke den Hollander's research group aims to understand the molecular disease mechanisms of common forms of vision loss, to determine which molecular factors can influence response to therapy, and to stratify patients for the most optimal therapy based on their molecular profile.

Genome bioinformatics

Christian Gilissen's group develops and applies bioinformatics methods to gain insight into the causes and mechanisms of genetic disorders such as intellectual disability.

Genomic technologies & immuno-genomics

Alexander Hoischen's research group focuses on the application of latest genomic technologies to understand human disease. A particular emphasis is put in the understanding of genetic defects that explain immune diseases, in particular primary immunodeficiencies.

Global health priorities

Rob Baltussen's research (sub)group supports decision-makers in countries around the world in setting legitimate priorities for universal health coverage.

Health technology assessment

Gert Jan van der Wilt's research group conducts research into the effectiveness, safety, efficiency and social acceptability of medical technology.

HTA business

Maroeska Rovers's research (sub)group aims to guide new medical technology innovations by facilitating partnerships between the scientific community, medical technology business partners and policy makers.

Intellectual disability & health

Geraline Leusink's research group has the mission to improve the health and healthcare for people with ID by integrating research, education and patient care.

Macular degeneration and ophthalmogenetics

Carel Hoyng's research group specializes in studying the genetics of retinal disorders. The two main research activities are age-related macular degeneration , a research program which has been started to develop better visual rehabilitation, and Ophthalmogenetics.

Magnesium in health and disease

Jeroen de Baaij's research group examines the role of magnesium in health and disease. Our mission is to decipher the pathophysiological mechanisms of magnesoium-wasting tubulopathies by development of novel disease models and advanced methods to measure magnesium transport.

Malaria research

Teun Bousema's, Robert Sauerwein's and Taco Kooij's research group focuses on the clinical development of plasmodium falciparum vaccines for control and elimination of malaria.

Medication safety

Cornelis (Kees) Kramers's research group aims to improve medication safety by education of prescribers, transmural interventions and medication optimization.

Molecular neurogenetics

Hans van Bokhoven's research group investigates the molecular underpinnings of development and functioning of the nervous system and its building blocks, the neurons and other cell types.

Molecular physiology

Joost Hoenderop’s group focuses on understanding tubulopathies. The focus is on the tubular transport of calcium, magnesium and sodium by the kidney tubule and the changes therein.

Motivational and cognitive control

Roshan Cools's research group aims to understand the neural and neurochemical mechanisms underlying flexible and adaptive behavior and decision making.

MRI-guided RFA therapy of liver and pancreatic tumors

Jurgen Fütterer's, Martijn Stommel's and Kristian Overduin's research group aims to assess the feasibility of real-time MRI temperature monitoring and ablation zone assessment during RFA of liver and pancreatic tumors.

MRI-guided Transurethral UltraSound Ablation

Jurgen Fütterer's research group performs MRI-guided Transurethral UltraSound Ablation (TULSA) in the prostate.

Nephropathology research group

Bart Smeets's research group aims to unravel the molecular processes underlying kidney regeneration and to identify new treatment targets to attenuate kidney disease progression.

Networks of memory and sleep

Lisa Genzel's group is interested in investigating how sleep influences memory processing in whole brain networks and which factors such as novelty experiences can influence this processing.

Neurological movement disorders

Bas Bloem's first research line aims at studying human motor control in health and disease, in particular patients with neurological movement disorders. A second main interest is in health care innovation, aiming to develop and scientifically evaluate patient-centred collaborative care.

Neuromuscular diseases

Baziel van Engelen's research group performs translational research on neuromuscular diseases.

Neurorehabilitation

Sander Geurts's research group conducts both translational and clinical studies with a focus on studies of motor control and functional recovery, particularly concerning balance and gait.

Orthopaedic research lab

Nico Verdonschot's research group focuses on the external loads applied to the musculoskeletal system, and how these loads influence the reconstructions.

Personalized pharmaceutical care

Bart van den Bemt's research group is a (inter)nationally recognized group on adequate medication use, medication adherence, medication waste and (cost-)effective pharmacotherapy.

Person-centered care, psychosocial and allied healthcare interventions

Maud Graff's research is focused on the effects of ccupational therapy at home for older individuals with mild to moderate cognitive impairments and their primary caregivers.

Pharmacogenomics

Marieke Coenen's research group performs pharmacogenetic research, from gene-finding to clinical implementation studies with a focus on paediatric (oncology) and psychiatry and inflammatory bowel disease.

Pharmacology and toxicology

Frans Russel's research group develops computational models that predict fetal-maternal drug exposure in pregnancy and brain penetration of drugs in adults and children.

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