Advanced X-ray Tomographic Imaging Lab (AXTI)
Ioannis Sechopoulos's research group focuses on novel image acquisition, processing and analysis techniques, physical and perceptual evaluation of image quality, radiation dosimetry, tomographic image reconstruction and advanced computational simulation methods in diagnostic x-ray based imaging.
Benno Roozendaal's research group investigates the brain processes underlying the effects of emotional arousal on memory processes. The goal is to increase understanding of traumatic memories in humans and develop new strategies for the prevention or treatment of memory- and anxiety disorders.
Cardiovascular physiology and exercise
Dick Thijssen's research group focuses on the field of cardiovascular physiology and physical (in)activity. His work strongly focuses on understanding the impact of exercise training and physical activity on reducing the risk of developing cardiovascular and metabolic diseases.
Dirk Schubert's research group aims to improve our understanding of the neural networks in the rodent primary somatosensory system and answer general questions about how altered gene expression or neuromodulators can affect cortical network organization and consequently behavior.
Cerebral circulation and cognition in aging humans
Jurgen Claassen's research group uses various techniques to measure cerebral perfusion, cerebral autoregulation and cognitive activation. These physiological mechanisms play an important role in Alzheimer’s disease, hypertension, and cognitive aging.
Cerebral circulation and cognition: Translational neurosciene
Amanda Kiliaan’s research group uses a multidisciplinary approach to study the link between (cerebro)vascular disorders and neurodegeneration. Within this group, neuroimaging is an important tool to study aspects of cerebral hemodynamics (e.g. cerebral blood flow/volume, vasoreactivity).
Clinical neuroscience in psychiatry
Indira Tendolkar's group focuses the intersection between clinical psychiatry and cognitive neuroscience with a focus on declarative memory. We investigate the adapatation of emotional and neutral memory processes depending on genetic and environmental variablity including somatic challenges.
Cognitive and affective neuroscience
Erno Hermans's research group investigates how neurochemicals affect diverse cognitive functions, such as vigilance, executive function, and memory. Moreover, they study how stressful experiences alter the intrinsic neural dynamics in the brain and how such processes contribute to memory.
Computational approaches to advance personalized medicine
Peter Bram 't Hoen's research group develops computational approaches that exploit molecular –omics data in combination with clinical data to better understand disease mechanisms and to advance patient diagnosis and stratification for therapeutic and life style interventions.
Jo Zhou's group aims to establish disease models using patient material and model organisms to identify regulatory networks and disease mechanisms in developmental disorders. Using genomics technology, we map the genome-wide atlas of disease-associated regulatory elements beyond the coding regions.
Disorders in impulse- and aggression regulation
Robbert-Jan Verkes's group aims to understand the neurobiological impairments in individuals with disorders in impulse- and/or aggression control. Particular interest in the influence on impulsive behavior of psychotropic compounds, including the individual differences in the effects of these drugs.
Drosophila models of brain disorders and neurogenetics
Annette Schenck's research focuses on dissecting molecular networks and mechanisms underlying human brain function and disease. In order to be able to investigate the large number of genes, we use a powerful genetic model organism, the fruitfly Drosophila melanogaster.
Engineered proteins for drug delivery
Wouter Verdurmen’s research group focuses on designing and investigating engineered proteins that overcome delivery barriers, employing synthetic binding proteins for target recognition. Various (super-resolution) microscopy techniques as well as microfluidic tumor-on-a-chip approaches are used.
Establishing physiological biomarkers of perioperative stress
Jurgen Fütterer's group conducts imaging and cognitive research at the intersection between clinical psychiatry and cognitive neuroscience with a focus forms of declarative memory that also play a role in development and maintenance of stress-related mental disorders.
Thijs Eijsvogels’s research group studies the acute and long-term effects of exercise on health. Current projects involve cardiac imaging following lifelong exercise training, optimizing cardiac rehab, assessing thermoregulatory responses in elite athletes and development of cooling strategies.
Genomic technologies & immuno-genomics
Alexander Hoischen's group focuses on the application of latest genomic technologies to understand human disease. A particular emphasis is put in the understanding of genetic defects that explain immune diseases, in particular primary immunodeficiencies (PIDs).