Cardiovascular physiology and exercise
Dick Thijssen's research group focuses on the field of cardiovascular physiology and physical (in)activity. His work strongly focuses on understanding the impact of exercise training and physical activity on reducing the risk of developing cardiovascular and metabolic diseases.
Cerebral circulation and cognition in aging humans
Jurgen Claassen's research group uses various techniques to measure cerebral perfusion, cerebral autoregulation and cognitive activation. These physiological mechanisms play an important role in Alzheimer’s disease, hypertension, and cognitive aging.
Clinical neuroscience in psychiatry
Indira Tendolkar's group focuses the intersection between clinical psychiatry and cognitive neuroscience with a focus on declarative memory. We investigate the adapatation of emotional and neutral memory processes depending on genetic and environmental variablity including somatic challenges.
Clinical pharmacology - special populations
Saskia de Wildt's research group uses innovative methods including microdosing and microtracer technology, and physiology-based and population pharmacokinetic modeling, to contribute to a better understanding of the impact of age, disease and genetics on drug disposition in children.
Cognitive and affective neuroscience
Erno Hermans's research group investigates how neurochemicals affect diverse cognitive functions, such as vigilance, executive function, and memory. Moreover, they study how stressful experiences alter the intrinsic neural dynamics in the brain and how such processes contribute to memory.
Computational approaches to advance personalized medicine
Peter-Bram 't Hoen's research group develops computational approaches that exploit molecular -omics data in combination with clinical data to better understand disease mechanisms and to advance patient diagnosis and stratification for therapeutic and life style interventions.
Establishing physiological biomarkers of perioperative stress
Jurgen Fütterer's group conducts imaging and cognitive research at the intersection between clinical psychiatry and cognitive neuroscience with a focus forms of declarative memory that also play a role in development and maintenance of stress-related mental disorders.
Thijs Eijsvogels’s research group studies the acute and long-term effects of exercise on health. Current projects involve cardiac imaging following lifelong exercise training, optimizing cardiac rehab, assessing thermoregulatory responses in elite athletes and development of cooling strategies.
Genetics of multifactorial eye diseases
Anneke den Hollander's research group aims to understand the molecular disease mechanisms of common forms of vision loss, to determine which molecular factors can influence response to therapy, and to stratify patients for the most optimal therapy based on their molecular profile.
Genomic technologies & immuno-genomics
Alexander Hoischen's research group focuses on the application of latest genomic technologies to understand human disease. A particular emphasis is put in the understanding of genetic defects that explain immune diseases, in particular primary immunodeficiencies.
Macular degeneration and ophthalmogenetics
Carel Hoyng's research group specializes in studying the genetics of retinal disorders. The two main research activities are age-related macular degeneration , a research program which has been started to develop better visual rehabilitation, and Ophthalmogenetics.
Magnesium in health and disease
Jeroen de Baaij's research group examines the role of magnesium in health and disease. Our mission is to decipher the pathophysiological mechanisms of magnesoium-wasting tubulopathies by development of novel disease models and advanced methods to measure magnesium transport.
Neurological movement disorders
Bas Bloem's first research line aims at studying human motor control in health and disease, in particular patients with neurological movement disorders. A second main interest is in health care innovation, aiming to develop and scientifically evaluate patient-centred collaborative care.