Non-healing wound in Nature Biomedical Engineering

Publication in the journal Nature Biomedical Engineering

Peter Friedl, theme Cancer development and immune defense and Eleonora Dondossola from MD Anderson Cancer Center joint-team apply intravital microscopy to visualize the foreign body response to implanted biomaterials in small animals. They show that neoangiogenesis drives chronic inflammation and scarring which was reverted by anti-angiogenesis therapy and macrophage depletion.  
 

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