Rob Aarnoutse associate professorRob Aarnoutse, PharmD PhD, is associate professor, hospital pharmacist and clinical pharmacologist, working at the Department of Pharmacy and with the Radboud Institute for Health Sciences at Radboudumc.
His research is focused on drug treatment of tuberculosis (TB), HIV and TB/HIV co-infection, the leading infectious disease killers worldwide. The central concept in his work is that efficacy and toxicity of drugs are dependent on drug concentrations achieved either systemically or locally. His research portfolio reaches from molecular pharmacological research to murine pharmacological studies, to pharmacokinetic studies in humans and clinical trials. In this way he develops a comprehensive translational research line that allows for quick application of relevant findings in the clinical setting. Typical topics of interest are adherence, pharmacokinetics, pharmacodynamics, safety/tolerability and effectiveness of TB drugs, antiretrovirals, other anti-infective drugs and immunosuppressants. His research is performed in The Netherlands, Indonesia, Tanzania, South Africa and other countries.
Rob Aarnoutse headed the Pharmacokinetic & Therapeutic Drug Monitoring Laboratory at Radboudumc for several years, is deputy director of education in hospital pharmacy for Radboudumc and is member of the Ethical Review Board Arnhem/Nijmegen. He has been active in various national boards for the Dutch Society of Hospital Pharmacists (NVZA) and for SKML. He is member of the Chief investigator Group of the Pan African Consortium for the Evaluation of Antituberculosis Antibiotics (PanACEA), is the chairman of the annual International Workshop on Clinical Pharmacology of Tuberculosis Drugs, and is otherwise well embedded in national and international gremia relevant to translational pharmacological research in the field of infectious diseases.
- Member of the Chief investigator Group of the Pan African Consortium for the Evaluation of Antituberculosis Antibiotics (PanACEA)
- Chairman of the annual International Workshop on Clinical Pharmacology of Tuberculosis Drugs
- Well embedded in national and international gremia relevant to translational pharmacological research in the field of infectious diseases
- Deputy director of education in hospital pharmacy for Radboudumc
- Member of the Ethical Review Board Arnhem/Nijmegen
Field of studyClinical Pharmacy
Research group Pharmacology of anti-tuberculosis drugs
Rob Aarnoutse's research group investigates the pharmacology of existing and new drugs for tuberculosis, using a translational approach that extends from molecular pharmacology to clinical pharmacology studies and to clinical trials, supported by advanced laboratory and modeling techniques.read more