The Board of NWO Domain Science has awarded in the NWO Open Competition Domain Science, Ronald van Rij, theme Infectious diseases and global health and Jennny van der Wijst, theme Renal disorders, an XS grant. The maximum funding is 50.000 euros per project. The XS category emphatically strives to encourage curiosity-driven and bold research involving a relatively quick analysis of a promising idea. As a pilot, applicants are also an assessor in the XS assessment process.
Ronald van Rij
Project: Defining the regulatory circuit that drives early development of virus-transmitting mosquitoes
Complex organisms are composed of a wide diversity of cell types, tissues, and organs, yet they all emerged from just a single fertilized cell. The very first steps in this developmental process are similar between different animal species, however, they can differ greatly at the molecular level. Early embryonic development has not been studied in the mosquito Aedes aegypti that is responsible for transmission of important epidemic viruses. In this project, the researchers will unravel genes that are essential for early development of this important mosquito species.
Project: Novel peptide therapeutic to fight kidney stones
Kidney stones affect around 1 in 10 people worldwide. It can be treated, but recurrence rates are high (>30%) resulting in increased risk of chronic kidney disease. An improved, possibly preventive treatment is needed. Our research aims to develop a novel drug to prevent kidney stone formation, based on our body’s calcium regulation. Calcium, obtained from our diet and essential for i.a. bone, can precipitate in our kidneys. This may lead to crystal formation, and ultimately kidney stone development. We propose to stop this process and prevent stone formation by local calcium buffering in the kidney via an original peptide-drug.
Related news items
ERC Starting Grant awarded to Jeroen de Baaij17 March 2022
Jeroen de Baaij, kidney researcher the Radboudumc, receives an ERC Starting Grant worth 1.5 million euros. He will use this grant to improve the diagnosis and treatment of severe magnesium deficiencies, which can lead to epileptic seizures and muscle cramps.read more
Laurens Verscheijden awarded doctorate degree 'cum laude'19 January 2022
Laurens Verscheijden of the Department of Pharmacology and Toxicology, defended his PhD thesis, entitled "Mechanistic models for the prediction of brain drug exposure and response in the paediatric population: A virtual child reaching maturation.read more
Academic collaboration agreement between UTwente and Radboudumc23 November 2021
The group of Biomaterials Science and Technology (BST) of the Faculty of Science and Technology at the TechMed centre of University of Twente has signed a formal academic collaboration agreement with the departments of Nephrology and Physiology at Radboudumc.read more
Four Veni grants for junior RIMLS researchers22 July 2019
Four junior researchers, affiliated to the RIMLS, have each received a Veni grant of 250,000 Euro from NWO. Our researchers received this prestigious grant for their remarkable and original talent and their ability to carry out innovative research.read more