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IgA nephropathy is a slowly progressing disease that causes kidney damage and leads to kidney failure in about 25-50% of patients. The reason why some people develop IgA nephropathy is unclear and there is no effective treatment.
Raphaël Duivenvoorden has now started a research project to unravel the cause of IgA nephropathy. It is of fundamental importance to gain a better understanding of the mechanisms leading to IgA nephropathy. The role of the gastrointestinal microbiome and immune cells in the bone marrow, are of particular interest for further research.
Therefore, in this research, Raphaël Duivenvoorden focuses on these two aspects to gain insight into how IgA nephropathy is caused. New insight into the cause of IgA nephropathy may contribute to the diagnosis of this disease and the development of targeted treatments. For more information, read here (in Dutch).
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