Aim of ActiveLIFE
More than half of the Dutch population does not engage in sufficient physical activity. ActiveLIFE aims to create one of the world’s largest dataset of objective accelerometry, allowing for further development and personalization of physical activity guidelines.
read moreAim of ActiveLIFE
The ActiveLIFE project will create world’s most comprehensive dataset of thigh-worn accelerometry, allowing detailed assessment of the relationship between physical (in)activity characteristics and health outcomes. For this purpose, 60,000 accelerometry measurements of 24-hour lifestyle behaviors will be combined with other extensive measurements (i.e. body composition, blood / urine / feces biomarkers, cognition, genetics, pulmonary function, physical capacity, electrocardiography, computed tomography) in the 4th assessment wave of the Lifelines Biobank study (www.lifelines.nl).
Latest news
- 10.000th accelerometry measurement collected!
- ActiveLIFE in the WHO report
- ActiveLIFE-LONG project granted

ActiveLIFE in the spotlights
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- Nieuws en Co op NPO Radio 1 (vanaf minuut 21)
- Hoe veel moet u bewegen? Advies op maat komt eraan | AD
- Helft van Nederlanders beweegt te weinig, maar is 150 minuten per week wel voor iedereen nodig? | AD
- Meer dan de helft van de Nederlanders beweegt te weinig, onderzoek naar richtlijn | NPO Radio 1
- 150 minuten bewegen, moet dat nou écht? | Margriet
- Grootste beweegonderzoek van Nederland van start | Nieuws en Co NPO Radio 1 (vanaf 21.30)
- 10.000 stappen is achterhaald | NOS
- Met 7.000 stappen per dag scoor je een 8 | Volkskrant
- Bij 7.000 stappen al minder kans op dementie, kanker en depressie | RTL
- Nederland blijft zitten: 'Risico op chronische ziektes neemt toe' | NPO Radio 1
- Grootste beweegonderzoek van Nederland van start | Moving Matters
- Geen sportschool, maar korte beweegsnacks tijdens de dag: werkt dat net zo goed? | de Volkskrant
- 'Dry January XXL': twee keer 45 minuten sporten per dag | NOS
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- Het onderzoek is begonnen - RTV Drenthe
- Grootste beweegonderzoek van Nederland van start | NPI
- Radboudumc start grootste beweegonderzoek van Nederland | De Brug
- Project ActiveLIFE, het grootste beweegonderzoek van Nederland van start gegaan | Zorgkrant
- Radboudumc start grootste beweegonderzoek van Nederland | Huisarts vandaag
- Grootste beweegonderzoek van Nederland van start | Goede Doelen
- Grootste beweegonderzoek van Nederland van start | Reuma Arnhem
- Grootste beweegonderzoek van Nederland van start | De Cardioloog
- Milou Netten - Bewegingsonderzoek | GL8 (radio)
- Grootste beweegonderzoek van Nederland van start | Nieuws voor leefstijlcoaches
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Tienduizend stappen niet zaligmakend, groot beweegonderzoek moet uitwijzen wat wel | RTV Drenthe
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Kleine stappen leveren grote gezondheidswinst op | De Eerste Lijns
- Gezondheidswinst meten bij 60 duizend proefpersonen | Vox

Collaboration
ActiveLIFE will be performed in collaboration with the Lifelines Biobank: a large, multigenerational, population-based cohort study in the Netherlands. This project is funded by the Dutch Ministry of Health, Welfare and Sport, the Dutch Heart Foundation, the Dutch Brain Foundation and Lung Foundation Netherlands.
Setting
ActiveLIFE will be performed in collaboration with the Lifelines Biobank: a large, multigenerational, population-based cohort study in the Netherlands that includes over 167,000 participants who will be followed for at least 30 years to obtain insight into (healthy) ageing and disease development. For this purpose, data are being collected with questionnaires, physical examinations, and bio samples since 2006. Given the broad collection of health-related parameters, its large sample size, deep phenotyping, and diversity, the Lifelines cohort is considered a unique international resource for high-quality and high-impact studies.
The 4th Lifelines assessment wave commenced mid-2024 and targets to measure 70,000 to 80,000 individuals within 5 years. Participants will visit the local Lifelines research center twice, separated by a time-window of 1-2 weeks. For ActiveLIFE, an accelerometer will be placed on the participant’s thigh during the first visit. Subsequently, the participant will wear the waterproof and nonobtrusive thigh-worn accelerometer for eight consecutive days to objectively and accurately assess physical (in)activity patterns. Raw data will be extracted and processed to generate a comprehensive set of 24-hour lifestyle behavior characteristics. Subsequently, we will enrich these data with prospective information on health outcomes (e.g. incident diseases and cause-specific mortality).

Accelerometry data
We anticipate to perform 60,000 accelerometer measurements in participants of the Lifelines Biobank study. Simultaneous assessment of thigh-worn and wrist-worn accelerometry measurements will be performed in ≈6,000 participants.
read moreAccelerometry data
We anticipate to perform 60,000 accelerometer measurements in participants of the Lifelines Biobank study. Simultaneous assessment of thigh-worn and wrist-worn accelerometry measurements will be performed in ≈6,000 participants. During their visit to the Lifelines research center, participants will undergo an extensive testing battery, including body composition, blood / urine / feces biomarkers, cognition, pulmonary function, physical function, and electrocardiography assessment as part of their enrolment in Lifelines. Following eight days of objective, habitual physical (in)activity assessment, the accelerometer will be returned, and raw data will be extracted, undergo quality control, and will be processed to produce aggregated outcomes for the Lifelines data catalogue.
Photo: Marieke van de Vegte.
Might be of interest
International advisory board
- Prof. dr. Francisco Ortega, University of Granada, Spain
- Prof. dr. Emmanuel Stamatakis, University of Sydney, Australia
- Prof. dr. Duck-chul Lee, University of Pittsburgh, USA

User committee
- Prof. dr. Martijn Spruit, Ciro, Maastricht University
- Prof. dr. Hidde van der Ploeg, Amsterdam UMC
- Prof. dr. Edo Richard, Radboudumc
- Dr. Annemarie Koster, Maastricht University
- Dr. Aernout Snoek, Vereniging voor Sportgeneeskunde, Isala
- Dr. Martijn Pisters, UMC Utrecht, Fontys University of Applied Sciences
- Dr. Yannick de Korte, Kenniscentrum Sport & Bewegen
- Dr. Barbara Snoeker, Rijksinstituut voor Volksgezondheid en Milieu
- Drs. Dorothee Laan, Beweegalliantie

Collaboration inquiries
Please contact the principal investigators for data availability inquiries and to explore collaboration opportunities in ongoing projects or future grant applications.
Our team
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Thijs Eijsvogels associate professor
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Esmée Bakker researcher in talent track Eerstelijnsgeneeskunde
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Milou Netten PhD candidate Fysiologie
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Sabine Schootemeijer postdoc

