Willemijn Hobo assistant professor
Willemijn Hobo is assistant professor at the Department of Laboratory Medicine. Her research interests include immunology and hemato-oncology, with a specific focus on the development and improvement of immunotherapeutic strategies to boost anti-tumor immunity in patients with hematological cancers.read more
Willemijn Hobo assistant professorResearch interests include immunology and hemato-oncology, with a specific focus on the development and improvement of immunotherapeutic strategies to boost anti-tumor immunity in patients with hematological cancers. Major current projects include the investigation of: 1) frequencies, phenotype and functionality of tumor-reactive T and NK cell responses in patients with hematological malignancies treated with immunomodulatory drugs and/or immunotherapy (including allogeneic stem cell transplantation, DC vaccination and adoptive T/NK transfer) 2) tumor immune escape mechanisms, including the involvement of co-inhibitory molecule signaling in functional impairment of tumor-reactive T cell responses & novel strategies to interfere with these suppressive mechanisms in the local tumor micro-environment; 3) exploration of dendritic cell vaccination & adoptive transfer strategies (NK cells and T cells) to boost anti-tumor immunity in cancer patients.
Willemijn Hobo is junior principal investigator at the Department of Laboratory Medicine – Laboratory of Hematology and coordinator of the Radboud Technology Center Flow cytometry. In addition, she is Deskundige ATMPs for manufacturing of cellular therapeutic products, and is involved as laboratory investigator in various clinical DC vaccination trials. She obtained her PhD in Medical Sciences Cum Laude in 2013 (Radboud University Nijmegen, the Netherlands). Her research studies are supported by grants of the KWF, ZonMW and Radboudumc/RIMLS.
Personal prizes & awards national & international
- 2016: Alpe d’HuZes Young Investigator Grant, research grant, Dutch Cancer Society, 2016, €617,250.
- 2016: Off-road grant, research grant, ZonMW, 2016, €125,000.
- 2015: €1750 grant by the René Vogels Foundation for work visit at the Antwerp University Hospital.
- 2014: $5000 George Santos award, Best clinical science article by a new investigator, American Society of Blood and Marrow Transplantation.
- 2013: €1000 Best thesis award of the Dutch Society for Immunology (NVVI), Noordwijkerhout.
- 2013: €1250 Travel Grant of the Dutch Society of Immunology (NVVI) for work visit at Yale University, New Haven, CT.
- 2012: Alpe d’HuZes Bas Mulder Award, research grant, Dutch Cancer Society, 2012, €600,000.
- 2010: PhD Award for best presentation at Dutch Tumor Immunology Meeting, Breukelen, the Netherlands.school Immunology
- Deskundige ATMPs for manufacturing of cellular therapeutic products
- Involved as laboratory investigator in various clinical DC vaccination trials
- Coordinator Radboud Technology Center Flow cytometry