About the department of Medical MicrobiologyAt the department of Medical Microbiology, we conduct diagnostic research and provide treatment advice. We work on tracking, diagnosing, and treating infectious diseases caused by microorganisms, e.g. by bacteria, viruses, parasites, and fungi.
Work methodIf a doctor or treating specialist suspects that an infection is the cause of an illness, they will have samples taken from the patient: blood, urine, excrement, swab test, biopsy, or cerebrospinal fluid. Our analysts will check whether this material contains microorganisms that cause infection and illness. Microorganisms include parasites, mold, yeasts, bacteria, and viruses. The medical microbiologist will discuss the results with the treating physician and make recommendations for treatment and any further diagnostics. Our infection prevention experts also ensure that the guidelines regarding the spread of (resistant) microorganisms are adhered to in our hospital and in the associated institutions in the environment. In this way, we prevent the microorganisms from spreading.
Research techniquesDepending on the clinical case of the patient, we will conduct a variety of research:
- Cultivation of bacteria or mold and examining their sensitivity to antibiotics.
- Detecting parasites using a microscope.
- Detecting microorganisms using molecular technology, such as a polymerase chain reaction (PCR).
- Serological testing to detect exposure to various microorganisms.
- Testing to detect antigens from microorganisms.
ISO accreditation quality certification markThe patient care laboratory of our department is ISO 15189 accredited: registration number M135. This means that the quality of our laboratory is regularly tested by an independent party (ISO) and they assess that the quality of our lab meets the applicable standards. go to website
Diagnostic operations in our medical handbook
In our laboratory, people can reference hundreds of different diagnostic operations. All Medical Microbiology diagnostic operations can be found in the Radboud university medical center e-lab guide.
Go to the e-lab guide
For some operations, we collaborate with other high-quality laboratories. In order to make the quality and competencies of our operations available for review, a statement of competencies for outsourced research has been created. You can download this and print it out for your administration.
Address and route
Radboudumc main entrance
Geert Grooteplein Zuid 10
6525 GA Nijmegen
Post addressP.O. Box 9101
6500 HB Nijmegen
Internal post 777
Our focus areas
Hygiene and Infection Prevention
The Hygiene and Infection team (HIP) advises healthcare departments in our hospital about preventing infections. This is important because the patients at Radboud university medical center have (temporarily) reduced immune resistance. They are susceptible to infection.read more
BacteriologyIn our bacteriology laboratory, we perform diagnostics in the field of bacterial infections. Medical microbiologists conduct many consults regarding the interpretation of testing and results. We also provide treatment recommendations to individual treatment providers and during multidisciplinary consultations. An example of this is daily antibiotic stewardship: discussion in collaboration with the internist-infectiologist and hospital pharmacists at our hospital.
Radboud university medical center is a tertiary referral center for orthopedic infections. For this reason, we pay a great deal of attention to improving on the diagnostics in this field as well as making them more efficient.
Special attention is given to correctly performing susceptibility testing and research into resistance development, including the use of whole genome sequencing.
Clinical virologyClinical virology provides rapid, adequate virological diagnostics and consultation for various patient groups inside and outside of Radboud university medical center. In addition to standard serological and molecular diagnostics for patients at the 1st, 2nd, and 3rd levels of care, virological diagnostics focuses on specific patient groups at the academic medical center:
- Immune-compromised patients (due to transplants, hematological malignancies, immune diseases, congenital disease, or medication).
- Patients with HIV and/or chronic hepatitis.
- Patient groups for which the Radboud university medical center operates as a knowledge center:
- The department of Medical Microbiology at Radboud university center, along with the AMC and the RIVM (National Institute for Public Health and the Environment) component of the Landelijk Expert Centrum Lyme (National Lyme expertise center). To do that, we perform high-quality diagnostics in the field of infections with Borrelia spp and we provide supporting consultation via a team of infectiologists and microbiologists.
- We conduct extensive Q-fever diagnostics in support of the Radboud Q-fever Expertise Center. This center was founded to optimize multidisciplinary care for (chronic) Q fever patients.
Medical parasitologyOur laboratory provides diagnostics into all parasitic infections. We have special expertise in the field of malaria diagnostics.
Malaria diagnostics entail:
- Suspicion of acute infection: CITO diagnostic (024-818 70 95) microscopy using QBC, thick smear, swab.
- Exclusion of exposure in the past: serology.
- Suspicion of very low infection (tropical splenomegaly syndrome): serology and PCR.
- Confirming positive microscopy or species: PCR.
Our infectiologists and medical microbiologists also offer consultative services for the support of diagnostics and treatment of tropical and parasitic infections.
MycobacteriologyIn the laboratory for Mycobacteriology, we provide all facets of clinical mycobacteriology. Our goal is to optimize the diagnostics and treatment of mycobacterial infections in both the Netherlands and abroad. In our laboratory, we conduct both cultivation and susceptibility testing for patient care and research under biosafety class 3 (BSL-3) conditions. In our laboratory, we are also able to work with other BSL-3 pathogens, e.g. Brucella species, Francisella species, and Histoplasma species.
We are a leading international laboratory in the field of susceptibility testing for non-tuberculosis mycobacteria (NTM) and in the cultivation of mycobacteria that are difficult to grow. Examples of these are Mycobacterium haemophilum and Mycobacterium genavense. We comply with all the relevant guidelines in this field and send our samples around Europe for quality control. We work closely with an international team of highly respected lung specialists, infectiologists, and medical microbiologists on providing consultative services to support the diagnostics and therapy of mycobacterial infections.
T (024)361 89 51
E for clinical inquiries: firstname.lastname@example.org
E for laboratory results TBuitslagen@mmb.umcn.nl