7 April 2017

Targeted therapies are a breakthrough in cancer treatment. The effectiveness of these therapies often depends on specific molecular tumor profiles. It is a challenge to predict which patients may benefit from these precision medicines. Therefore the PATH project was initiated: Predictive Analysis for THerapy.

My name is Lieneke Steeghs. I recently started as postdoc at the department of Pathology to work on the PATH project under supervision of dr. Marjolijn Ligtenberg and dr. Katrien Grünberg. Targeted treatment options and predictive diagnostic genetic markers are rapidly expanding. The PATH project aims to optimize access to these precisions medicines for cancer patients in the Netherlands.

More than 30 pathology departments in the Netherlands participate in this multi-center study. Via a close collaboration between pathology departments and treating physicians (medical oncologists, pulmonary oncologists) we aim to build a nationwide infrastructure to implement and evaluate innovative genomic cancer diagnostic opportunities in clinical cancer care. In order to achieve this goal predictive tumor genetic diagnostics will be optimized, a national expert network will be built, and the clinical utility will be studied. Targeted therapies are a breakthrough in cancer treatment. The effectiveness of these therapies often depends on  specific molecular tumor profiles. It is a challenge to predict which patients may benefit from these precision medicines. Therefore the PATH project was initiated: Predictive Analysis for THerapy.

Lieneke Steeghs
 
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