18 September 2017

Nicole Visser is resident of pathology and she is working on a PhD project to improve the pre-operative recognition of high risk endometrial carcinoma.

Endometrial carcinoma is the most common gynecologic malignancy in industrialized countries and the incidence is still rising. Primary treatment is based on preoperative risk classification, but in routine clinical practice final histology regularly does not correspond with the preoperative histological diagnosis. This results in both over and under treatment. In collaboration with nine hospitals in the OOR-ON region, prospectively clinical and histological data are collected of 432 patients with endometrial carcinoma. The aim of this PIpelle Prospective ENDOmetrial carcinoma (PIPENDO) study is to select a panel of prognostic biomarkers to improve preoperative diagnosis of endometrial carcinoma in order to identify those patients that need extended surgery and/or additional treatment. This study illustrates the importance of collaboration of university hospitals with general hospitals, where most patients with endometrial carcinoma are treated. The PIPENDO study is one of several ongoing project on endometrial cancer in Women’s Cancer theme.

Congratulations for Nicole Visser from her research colleagues Louis van der Putten, Casper Reijnen and Hanny Pijnenborg. 

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