In British Journal of Radiology Rutger Stijns and colleagues, theme tumors of the digestive tract, showed that using MRI with endorectal filling did not lead to an improved rectal cancer staging and that it has the potential to influence the distance to a key anatomical landmark.ABSTRACT
To assess the influence of endorectal filling (EF) on rectal cancer staging.
47 patients who underwent a staging MRI of rectal cancer in the period from 2011 to 2014 were included. The MRI protocol included T2 weighted fast spin echo sequences without and with EF at 3 T (EF-MRI). Images were scored by two readers for T-stage, distance of the lower pole of the tumour to the anorectal junction, distance to the mesorectal fascia (MRF), and number of (suspicious) lymph nodes. Agreement in T-staging was calculated using the Cohen's κ value. Comparison of continuous variables was performed using Wilcoxon matched pairs signed-rank test.
The interobserver agreement for T-staging with and without EF-MRI showed a poor agreement between both readers (weighted κ = 0.156, weighted κ = 0.037, respectively). Tumours tended to be overstaged more prominently with EF-MRI. The accuracy of predicting the pathological T-stage slightly improved from 55% with EF to 64% without EF for Reader 1 and from 59 to 68% for Reader 2, respectively. The distance of the tumour to the anorectal junction increased from 33.9 to 49.3 mm (p < 0.001) after EF for Reader 2. EF-MRI did not significantly influence the number of (suspicious) lymph nodes and distance to the mesorectal fascia.
EF-MRI did not lead to an improved tumour staging and it has the potential to influence the distance to a key anatomical landmark. EF-MRI is therefore not recommended in primary staging rectal cancer. Advances in knowledge: EF-MRI may not be used as an additional tool to stage rectal cancer patients, as it does not seem to facilitate in locoregionally staging the disease.
The influence of endorectal filling on rectal cancer staging with MRI.
Stijns RC, Scheenen TW, de Wilt JH, Fütterer JJ, Beets-Tan RG.
Want to know more about these subjects? Click on the buttons below for more news.
Related news items
Mathias Prokop appointed department head of Radiology UMCG He also remains department head of Imaging Radboudumc11 April 2022 As of May 1, Mathias Prokop will become Department Head of Radiology at UMCG. He will fulfill this role in addition to his current position as Professor and Department Head of Imaging at the Radboudumc. Jurgen Fütterer will assume the daily management of the Radboudumc clinic. read more
Thomas van den Heuvel wins Stairway to Impact Award for safer pregnancies using AI Award for safer pregnancies using AI1 December 2021
Radboudumc researcher Thomas van den Heuvel receives the Stairway to Impact Award from Dutch Research Council NWO. He receives this prize for the development of the BabyChecker, a smartphone application that allows midwives to make ultrasounds during pregnancies.read more