Lifestyle habits and bladder cancer prognosis: effects by tumour stage and molecular subtype.
Non-muscle invasive bladder cancer patients (NMIBC) with T1 tumours or genomically unstable/squamous-cell-carcinoma-like molecular subtypes have a high risk of recurrence and muscle-invasive progression, the latter being a life-threatening condition. This project will provide insight in whether associations of smoking, body weight, physical activity, and fruit and vegetable consumption with NMIBC outcomes are mediated and/or modified by tumour stage and molecular subtype. Our ultimate aim is to provide NMIBC patients with tailored advice concerning their lifestyle to enable them to influence their prognosis.
Collaboration between Radboudumc (Project Leader Alina Vrieling, Principal Investigator Bart Kiemeney) and Erasmus MC (Principal Investigator Dr. Arno van Leenders)
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