29 April 2019

Polycystic liver disease is the most common extra-renal manifestation of autosomal dominant polycystic kidney disease (ADPKD). There is need for robust long-term evidence for the volume-reducing effect of somatostatin analogues.

Joost Drenth, theme Renal disorders, and colleagues, made use of data from an open-label, randomized trial to determine the effects of lanreotide on height-adjusted liver volume (hTLV) and combined height-adjusted liver and kidney volume (hTLKV) in patients with ADPKD. 

In this trial of patients with polycystic liver disease due to ADPKD, lanreotide for 120 weeks reduced the growth of liver and combined liver- and kidney volume. This effect was still present 4 months after the last injection of lanreotide. They have published their findings in the journal Gastroenterology.


 

Related news items


Online intervention for women exposed to intimate partner violence

21 November 2019

Within the SAFE project from the department of Primary and Community Care an eHealth intervention has been developed for women exposed to intimate partner violence (IPV).

read more

A personal touch of Sander Leeuwenburgh

21 November 2019

In order to promote interaction amongst colleagues within RIMLS, we have a ‘personal touch’ series setting employees in the spotlight. A light-hearted manner to learn about the colleagues you know and those you don’t. This week: Sander Leeuwenburgh.

read more

Technology for Oncology II grant application funded

21 November 2019

The grant application called "aiREAD – Accurate and Intelligent Reading for EArlier breast cancer Detection” by project leader Ioannis Sechopoulos, has been selected for funding under the NWO TTW – KWF Kankerbestrijding – Top Sector LSH Partnership “Technology for Oncology II”.

read more

KNCV Golden Master Award call for nominations

20 November 2019

The Royal Netherlands Chemistry Society awards this prize each year to the best Master’s research project. The Master’s thesis must relate to research in the field of chemistry, life sciences, process technology or (bio-)molecular sciences. Deadline: 31-12-2019.

read more

Podosome nanoscale architecture redefined

20 November 2019

Koen van den Dries and Alessandra Cambi, theme Nanomedicine, revealed how the nanoscale architecture of podosomes enables dendritic cells to protrude and sense their extracellular environment. They have published their results in Nature Communications.

read more

270 times Homo Universalis in Nijmegen

20 November 2019

What does a scientist of the future look like? International young scientists addressed this important topic during the ENABLE conference, organized by young researchers for young researchers. They showed how the new generation of researchers wants to open up science to the public.

read more