17 January 2020

Dermatology Radboudumc and Dermatology Ghent received a grant of 1.6 million euros for investigating dose reduction of the newest biologics for psoriasis.

The BeNeFIT (Belgium-Netherlands Funding of International Trials) program, in which ZonMw and the Belgian KCE have joined forces, has honored the first two grant applications. One of these is a study into the dose reduction of biologics in psoriasis, carried out by Elke de Jong and Juul van den Reek and UZ Gent, Jo Lambert and Lynda Grine. Reduction of new generation biologics in psoriasis. This awarded project concerns research into dose reduction of new generation biologics in psoriasis. Biologics are very effective agents for the treatment of psoriasis. Previous research has shown that the dose of TNFα-blocking biologics can be reduced in some patients. For the new generation of biologics, IL17 and IL23 inhibitors, it is not yet known whether dose reduction of these agents is possible. The new agents have different mechanisms and safety profiles in comparison with TNFα blockers and are increasingly prescribed. It is therefore important to investigate the possibilities for dose reduction of these new biologics in a timely manner.

ZonMw and KCE granted 1.6 millon euros to perform this large multinational study in 17 hospitals in Belgium and the Netherlands. 

Related news items


Grants for heart and kidney research Two awards to Radboudumc in Open Competition ENW-XS

21 July 2022

Two researchers from the Radboudumc receive a grant from the NWO within the Open Competition of the Exact and Natural Sciences. They are Thijs Eijsvogels, who studies the heart, and Pieter Leermakers, who studies the kidneys. 

read more

More than five million euros for research to improve palliative care Jeroen Hasselaar will lead research project with Horizon grant

15 June 2022 Jeroen Hasselaar will lead a large international research project. With a 5.3 million euro grant from the EU's Horizon program, he and his team want to improve palliative care for cancer patients, together with partners from nine European countries. read more

Benjamin Wendt wins the Anna Reynvaan Science Prize 2022 prize for research into application of infection prevention measures in district nursing

16 May 2022 On May 12, de Dag van de Verpleging, Benjamin Wendt won the Anna Reynvaan Science Prize 2022. This prize is awarded annually for the best scientific publication by a nurse from the previous year. read more

Large NWA ORC grant awarded for national skin research: Next Generation ImmunoDermatology

23 March 2022 Research for better treatment methods for chronic skin diseases. read more

ZonMw grants to study optimal use of COVID-19 vaccines in patients with impaired immune systems

3 February 2021 How do people with reduced immunity, especially kidney patients, react to a COVID-19 vaccination? And how can patients with peripheral arterial disease be helped by DNA testing? Our researchers received grants from ZonMw to make these studies possible. read more

Tight controlled dose reduction of biologics in psoriasis patients

7 May 2020 Published in JAMA Dermatology, RIHS researcher Selma Atalay and colleagues investigated in a randomized controlled trial a tight controlled dose reduction strategy of the biologics adalimumab, etanercept and ustekinumab in psoriasis patients. read more