Biomarkers found in COVID-19 patients support bradykinin hypothesis29 May 2020
A study into inflammatory substances in the blood of COVID-19 patients supports the hypothesis that kinins could play a role in the respiratory problems experienced by critically ill COVID-19 patients in IC. This discovery, published at MedRxiv, could lead to the development of new treatments.
Introducing OnePlanet Research Center webinar 5 June, 16:00 hrs.29 May 2020
OnePlanet Research Center develops digital technologies to create a society in which everyone can live a healthy life and has access to healthy and sustainable food. Radboudumc and Radboud University are amongst the founding partners. Find out what OnePlanet can do for you in this online session.
The impact of sex and gender in the COVID-19 pandemic29 May 2020
The case study of Sabine Oertelt-Prigione, developed by the European Commission’s H2020 Expert Group to update and expand "Gendered Innovations/Innovation through Gender", examines the impact of sex and gender in the current COVID-19 pandemic.
Evaluation of an AI system for detection of COVID-19 on Chest X-Ray images22 May 2020
In the journal Radiology researchers from Radboudumc, Bernhoven Hospital and Jeroen Bosch Hospital described how an artificial intelligence system (CAD4COVID-XRay) can identify characteristics of COVID-19 on chest x-rays with performance comparable to six independent radiologists.
Intra-articular corticosteroid injections increase the risk of requiring knee arthroplasty14 May 2020
In The Bone & Joint Journal, RIHS researcher Stan Wijn et al. showed that corticosteroid injections in the knee joint are associated with an increased risk of knee arthroplasty in patients with, or at risk of developing, symptomatic osteoarthritis of the knee.
Dolutegravir versus efavirenz in women starting HIV therapy in late pregnancy (DolPHIN-2)12 May 2020
In Lancet HIV RIHS researchers Angela Colbers and David Burger showed in an open-label, randomized controlled trial, that, when initiated in the 3rd trimester of pregnancy, achievement of VL <50cp/mL at delivery was more likely with dolutegravir-based therapy than with efavirenz-based regimens.
Early symptoms in Radboudumc healthcare workers who were tested for SARS-CoV-212 May 2020
In Eurosurveillance RIHS researcher Alma Tostmann and colleagues from the Radboudumc COVID-19 Team describe that general symptoms like fever, headache, general malaise and muscle ache were associated with a positive SARS-CoV-2 test. Respiratory symptoms however, were not predictive for SARS-CoV-2.
Tight controlled dose reduction of biologics in psoriasis patients7 May 2020
Published in JAMA Dermatology, RIHS researcher Selma Atalay and colleagues investigated in a randomized controlled trial a tight controlled dose reduction strategy of the biologics adalimumab, etanercept and ustekinumab in psoriasis patients.
Save the date for Radboud New Frontiers 2020 Prevention: the need for a leap forward23 April 2020
Although it is uncertain in what format the symposium can be organized, we continue with the preparation of the yearly Radboud New Frontiers symposium on 12 November 2020. This year’s topic is prevention. Save the date already!
A new treatment option for an antibiotic nightmare23 April 2020
Lung infections by Mycobacterium abscessus are emerging worldwide and are difficult to treat, because of the bacterium’s resistance. The group led by Jakko van Ingen discovered that inhalation of an old and normally toxic antibiotic may finally improve treatment outcomes of this severe infection.
Martin Boeree appointed as professor of Clinical Tuberculosis and other Mycobacterial Diseases23 April 2020
Martin Boeree is searching for shorter and better treatments for drug sensitive and resistant tuberculosis. He is also conducting interdisciplinary research on treatment and clinical relevance in the area of non-tuberculous mycobacteria.
Study on effect of BCG vaccine on coronavirus infection in the elderly21 April 2020
Radboud university medical center and UMC Utrecht are working on a joint research project to discover whether the tuberculosis (BCG) vaccine reduces the risk of infection with the coronavirus in people aged 60 or older, or the severity of the symptoms in the event of infection.
Webinar for researchers Wednesday 22 April, 20:00 hrs17 April 2020
The corona crisis has an impact on research every day. This webinar is specifically aimed at researchers. Do you have specific topics or questions that you would like to see reflected in the webinar? Let us know via email@example.com.
Radboudumc researchers publish new insights into COVID-19 Consequences for treatment are now being examined internationally10 April 2020
Researchers at the Radboud university medical center seem to have found an essential mechanism in the disease process of Covid-19, which has so far been overlooked. If the insight is correct, it probably has important consequences for the treatment of the disease.
Dealing with COVID-19 in low- and middle-income countries26 March 2020
RIHS researcher Joost Hopman believes that low-and middle-income countries should intensify their preparedness for a possible COVID-19 outbreak. This was the core message of an opinion article that he wrote at the request of the medical journal JAMA.
Physiotherapy is important to the recovery of patients with the coronavirus26 March 2020
Patients who have been infected with the coronavirus and admitted to the hospital for this reason should receive physiotherapy as soon as their condition allows. This is the view expressed by physiotherapists and researchers from the Radboudumc in a set of joint treatment recommendations.
Healthcare utilization and regional variation of end-of-life hospital care in Dutch cancer patients26 March 2020
In International Journal of Quality Health Care RIHS researcher Femke Atsma showed high healthcare utilization and medical variation in End of Life care in Cancer patients, which was not associated with GP care or long term care.
Study into better protection for healthcare workers against coronavirus infection19 March 2020
Radboudumc and UMC Utrecht will investigate whether health care workers are better protected against the coronavirus after a vaccination against tuberculosis (BCG vaccine). This vaccine does not directly protect against the coronavirus, but provides a boost to the immune system.
Differences in the placental disposition of TNF inhibitors uncovered19 March 2020
In Clinical Pharmacology and Therapeutics, researchers from the Depts. of Pharmacology and Toxicology, Obstetrics and Gynecology, and Health Evidence, in collaboration with Sanquin Diagnostic Services, investigated the placental handling of the TNF inhibitors infliximab and etanercept.
The effect of pregnancy on the pharmacokinetics of dolutegravir in women living with HIV17 March 2020
In Clinical infectious diseases RIHS researchers Pauline Bollen, Jolien Freriksen, Angela Colbers and David Burger together with researchers of the PANNA network showed that dolutegravir use in pregnancy results in effective plasma concentrations.
Greater attention to sex and gender needed in healthcare13 March 2020
Scientific research shows that both sex and gender influence health behavior and impact disease development, having an effect on its diagnosis, treatment, and long-term effects as well. That is what RIHS researcher Sabine Oertelt-Prigione states in The Lancet EClinical Medicine.
Electronic nose smells precursor of oesophageal cancer5 March 2020
A portable electronic nose can effectively detect precursors of oesophageal cancer, reported by RIHS researchers Yonne Peters and Peter Siersema in the medical science journal GUT. This was demonstrated in an initial study involving more than four hundred patients.
Prevention of tuberculosis among people with diabetes the first clinical trial globally5 March 2020
In recent years it has become clear that diabetes is an important factor driving the global tuberculosis epidemic. Diabetes also leads to more severe and recurrent disease and more TB deaths. The first clinical trial to prevent TB among people with diabetes will be started by the PROTID consortium.
Plugging the gap ZonMw/Health Holland grant3 March 2020
RIMLS en RIHS researchers Willeke Daamen, Frank Vandenbussche, Joris van Drongelen, Toin van Kuppevelt and Janneke Grutters have been granted 1.3 million euro for the development and evaluation of a new technology to prevent premature rupture of fetal membranes (iPPROM).
People-like-me treatment for intermittent claudication Personalized approach for patients27 February 2020
Radboudumc, with the University of Colorado, ClaudicatioNet and Harteraad, has developed a method to better treat people with intermittent claudication. This method, by RIHS researcher Thomas Hoogeboom among others, enables physiotherapists to coordinate the care process with the patient better.
Guiding the surgeon real-time tumor visualization during surgery26 February 2020
Incomplete excision of tumor tissue negatively affects the prognosis of the patient. RIHS researcher Mark Rijpkema and colleagues are working on the development of new dual-labeled tracers and currently are implementing this into the clinic.
Jurgen Fütterer appointed Professor of Image-Guided Oncological Interventions26 February 2020
RIHS researcher Fütterer is an interventional radiologist and an expert in the field of cancer imaging techniques, image-guided interventions and robotics. He is also Professor at the Robotics and Mechatronics Group at the University of Twente.
Dutch Brain Foundation grant for EENnacoma20 February 2020
Lavrijsen and Van Erp: ‘This grant will facilitate practice-based research, professionalization and further academization of EENnacoma, and links between different health care and research institutions all for the benefit of people with prolonged disorders of consciousness and their families.'
RIHS Awards Ceremony five winners19 February 2020
On 18 February the RIHS 'Koek & Zopie' event took place. In front of an audience of more than 125 colleagues, RIHS awardees accepted their awards for the best PhD thesis, the research product with the highest impact on society, the best peer-reviewed publication and the Supervisor of the year 2019.
KNAW Early Career Award for Geert Litjens13 February 2020
Twelve young researchers received the Early Career Award from KNAW on 4 february. One of them is RIHS researcher Geert Litjens. The Award is aimed at researchers in the Netherlands at the start of their career who are capable of developing innovative and original research ideas.
Interactive career day for Postdocs and PhD candidates13 February 2020
45 Postdocs and PhD candidates attended the first Interactive career day organised by Janssen Pharmaceutica, to learn more about career perspectives and R&D activities that on the longer term can lead to ideas and potential future collaboration.
SPL Medical starts clinical trial with contrast agent ferrotran11 February 2020
SPL Medical is starting an international registration study for its contrast agent Ferrotran. The study is being conducted in ten hospitals in Germany, Switzerland and the Netherlands. RIHS researcher Jelle Barentsz discovered the value of this drug in patients with lymph node metastases.