Magnesium in health and disease
Jeroen de Baaij's research group examines the role of magnesium in health and disease. His team studies the regulation of magnesium handling by the intestine and the kidney, as well as the role of magnesium in disease including diabetes mellitus type 2 and chronic kidney disease.
Renal electrolyte handling
René Bindels' research group studies the regulation of ion transport processes in kidney and small intestine in health and disease. Current projects involve the molecular mechanisms underlying rare tubulopathies and the regulation of the newly identified calcium, magnesium and sodium transporters.
Roland Brock’s group focuses on the targeted delivery of molecules such as oligonucleotides, toxins and photosensitizers to modulate cell function and/or induce cell death. This research involves fundamental studies of formulation strategies and uptake mechanisms as well as preclinical applications.