About Pediatric respiratory infection and immunity
We are dedicated to advancing pediatric respiratory health by studying the mucosal immune system of the respiratory tract in vulnerable pediatric populations, drawing on long-standing collaborations with South Africa and the Caribbean part of the Kingdom of the Netherlands.
Publications
See the publication list of the research group leader on Web of Science.
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- S Engels, MEC Tilanus, JJ Euson, N Stastny, C Maria, S Baboe-Kalpoe, F Baboe, CKA Fleming, S Carty-Fleming, S Holaman, K Baan, F Holiday, SCF van den Borne, RF Plantinga, RP Wong Chung, JS van de Maat, MI de Jonge, R Steingrover, LM Verhagen. Association between common pathogens and disease severity, and pathogen specific seasonality in the Caribbean pre- and post-COVID-19: a retrospective study. BMJ Open 2026;16(1):e104991.
- C Maria, J Kalpoe, AT Tromp, F Koene, D Souverein, S van Roeden, M Tilanus, J Juliet, M Euson, S Carty, S Holaman, S Baboe-Kalpoe, F Baboe, R Plaisier, C Oliveira Dos Santos, A Visser, W van Luling, F Holiday, C Fleming, J van de Maat, PK Klouwenberg, R Steingrover, LM Verhagen. Seasonal dynamics of influenza and RSV in the Caribbean: A call for regionally tailored preventive measures. Int J Infect Dis 2026:166:108498.
- EAML Mutsaerts, B van Cranenbroek, SA Madhi, E Simonetti, A Arns, L Jose, A Koen, AE van Herwaarden, MI de Jonge, LM Verhagen. Impact of nutritional status on vaccine-induced immunity in children living in South Africa: investigating the B-cell repertoire and metabolic hormones. Vaccine 2024; Apr 17:S0264-410X(24)00448-1.
- A Redfern, MM van der Zalm, J Lishman, P Goussard, L Smit, R Dagan, M Barday, M Mare, M Claassen, G van Zyl, H Rabie, LM Verhagen. Clinical presentation and outcome of acute respiratory illnesses in South African children during the COVID-19 pandemic. Pediatr Infect Dis J 2023;42:672-8.
- H Wang, X Li, Y Zheng, LM Verhagen, J Gu, L Li, Z Xu, W Wang, MI de Jonge. Concordance in pathogen identification at the upper and lower respiratory tract of children with severe pneumonia. BMC Infect Dis 2023;23:170.
- KE Siegers, AE van Herwaarden, JH de Waard, B del Nogal, PWM Hermans, D van Tienoven, GAM Berbers, MI de Jonge, LM Verhagen. The metabolic hormone adiponectin affects the correlation between nutritional status and pneumococcal vaccine response in vulnerable indigenous children. PLoS ONE 2022;e0270736.
- Mwape RK, Barday M-A, van der Zalm MM, Verhagen LM. Overview of mucosal immunity and respiratory infections in children: a focus on Africa. Curr Opin Pediatr 2025;37(2):137-144.
- MH Koenen, WAA de Steenhuijsen Piters, MI de Jonge, JD Langereis, S Nierkens, MLJN Chu, R van der Woude, RP de Vries, EAM Sanders, D Bogaert, E van der Vries, M Boes, LM Verhagen. Salivary polyreactive antibodies and Haemophilus influenzae are associated with respiratory infection severity in young children with recurrent respiratory infections. Eur Resp J 2024;64(4):2400317.
- MH Koenen, RCA de Groot, WAA de Steenhuijsen-Piters, MJLN Chu, K Arp, R Hasrat, ACJM de Bruijn, SC Estevao, E van der Vries, JD Langereis, M Boes, D Bogaert, AMC van Rossum, WWJ Unger, LM Verhagen. Mycoplasma pneumoniae carriage in children with recurrent respiratory tract infections is associated with a less diverse and altered microbiota. eBioMedicine 2023;98:104868.
- MM van der Zalm, NA Sam-Agudu, LM Verhagen. Respiratory adenovirus infections in children: a focus on Africa. Curr Opin Pediatr 2024; 36(3):342-48.
Internationally we are also known as
PedResp Group
Research programs
Programs that are connected to this research group.
Our members
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Josephine van de Maat arts in opleiding tot kinderarts
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Myrthe Reiche postdoc Laboratoriumgeneeskunde
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Sam Engels PhD candidate Laboratorium Medische Immunologie