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Our purpose
The overarching aim of the research program is to understand the function and the regulation of innate immune system in health and disease, and to perform research towards development of diagnostic and therapeutic strategies targeting innate immunity.
Goals
- To study innate immune responses is at population level, through the integration of deep immunological phenotyping with various layers of omics: genomics, epigenomics, transcriptomics, metabolomics, proteomics.
- To understand the innate immune-based mechanisms that contribute to the pathophysiology of diseases (infections, inflammatory diseases, such as atherosclerosis, gout, and cancer).
- To improve efficacy of vaccines against several microorganisms using trained immunity.
- To explore optimize the use of innate immune mechanisms (e.g. recombinant cytokines, trained immunity) for immunotherapy of cancer, infections and inflammatory diseases.
Research group leaders
See which research group leaders (RGLs) contribute to this research program.
read moreResearch group leaders
Our programs form inspiring environments in which research groups work together toward a common and clear goal, enabling our researchers to strenghten collaboration and cross thematic and disciplinary boundaries. Within and outside Radboudumc.
RGLs contributing to this research program
- Reinout van Crevel
- Baziel van Engelen
- Alexander Hoischen
- Marien de Jonge
- Leo Joosten
- Saskia Middeldorp
- Benjamin Mordmüller
- Willem Mulder
- Mihai Netea
- Peter Pickkers
- Niels Riksen
- Raphaël Duivenvoorden
- Cees Tack
- Frank van de Veerdonk
- Michiel Warlé
In the near future, we plan to link specially designed research group pages instead of these profile pages.
