NL
DE
Our mission
We aim to understand the function and the regulation of the innate immune system in health and disease and to perform research towards development of diagnostic and therapeutic strategies targeting innate immunity.
Goals
- To study innate immune responses at population level through systems biology integration of deep immunological phenotyping with (epi)genomic, metagenomic, transcriptomic, metabolomic and proteomic information.
- To understand the innate immune-based mechanisms that contribute to the pathophysiology of immune-mediated diseases, particularly infections, inflammatory diseases and cancer.
- To improve efficacy of vaccines against several microorganisms using trained immunity.
- To explore and optimize the use of innate immune mechanisms (e.g. recombinant cytokines, trained immunity nanobiologics) for immunotherapy of cancer, infections and inflammatory diseases.
