About
We aim to unravel the cortico-striatal computations and dynamics by which behavioral control strategies are adaptively tuned to our changing environment, in mental health and disease.
Aims
Much of our work focuses on the affective and decision functions of the ascending neuromodulators, of dopamine, serotonin and noradrenaline, which we have established depend critically on current task context, and associated brain circuits. To study these functions, we integrate cognitive, clinical, and computational neuroscience and combine neuroimaging, pharmacology, and brain stimulation in healthy people and people with brain disorders like Parkinson’s disease and major depressive disorder. The work has implications for understanding the mechanistic basis and predicting treatment effects in a variety of mental health conditions.
Research programs
Programs that are connected to this research group.