Infrastructure

Research Radboudumc Technology Centers Preclinical imaging

About

We offer advanced preclinical and molecular imaging – including in vivo, ex vivo, and postmortem imaging of both human tissue and small animal models –, and behavioral analyses.

Contact

prof. dr. Amanda Kiliaan PhD
RTC coordinator

+316 16 26 25 88

Expertises and services

Let us enhance your research

See what makes us unique and why we are (inter)nationally recognized on preclinical and molecular imaging.

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Let us enhance your research

We offer advanced preclinical and molecular imaging – including in vivo, ex vivo, and postmortem imaging of both human tissue and small animal models –, and behavioral analyses.

We uniquely integrate high-resolution imaging technologies with behavioral and cognitive testing facilities on one floor. This combination enables researchers to correlate structural, functional, and molecular imaging data with behavioral outcomes, making us one of the most comprehensive preclinical research environments in Europe.

As a mixed node of Euro-BioImaging combining biomedical imaging and microscopy, we offer both preclinical and molecular imaging capabilities. RTC Preclinical imaging is the only facility in the Netherlands housing more than eight imaging modalities under one roof, supporting longitudinal, multimodal, and translational studies.

PRIME

This RTC also operates under the already nationally and internationally recognized name "PRIME" (abbreviation of Preclinical imaging center).

[If you have multiple types of expertises and services, you can use multiple accordion items to showcase each one of them. Or you can cluster expertises and services by theme within different accordion items. Preferably, you give very short information for each expertise here and you link to a bigger web page about that service, if available. But you can also choose to elaborate in full on a specific expertise or service within an accordion item.]
[If you have multiple types of expertises and services, you can use multiple accordion items to showcase each one of them. Or you can cluster expertises and services by theme within different accordion items. Preferably, you give very short information for each expertise here and you link to a bigger web page about that service, if available. But you can also choose to elaborate in full on a specific expertise or service within an accordion item.]

Our expertises

We operate with a multidisciplinary team with deep expertise in imaging science, animal research and translational therapies.

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Our expertises

We operate with a multidisciplinary team with deep expertise in imaging science, animal research and translational therapies.

Extensive experience with MRI, PET/CT, SPECT/CT, ultrasound, optical imaging, photo-acoustics, and multiphoton microscopy.
Preclinical radiotherapy applications, including treatment planning and combination therapy studies.
Design, synthesis, and application of novel imaging agents for molecular and functional imaging.
Integration of imaging with cognitive and behavioral assessments in small animal models.
Advanced pipelines for image registration, segmentation, and multimodal data fusion.
Bridging preclinical and clinical research through harmonized imaging protocols and shared infrastructure.
Active participation in national and international networks, including Euro-BioImaging, with a strong track record in collaborative projects.

Our services

We provide cutting-edge technology for imaging-related preclinical research and support both academic and industrial partners.

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Our services

We provide cutting-edge technology for imaging-related preclinical research and support both academic and industrial partners.

Strategic advice on study design, modality selection, and translational relevance.
Collaborative and commissioned studies using advanced imaging platforms.
Longitudinal and multimodal imaging in mice and rats, including behavioral assessments.
Tailored imaging protocols for specific biological questions and disease models.
Access to a broad range of imaging modalities:
- Magnetic Resonance Imaging (MRI)
- Positron Emission Tomography / Computed Tomography (PET/CT)
- Single Photon Emission Computed Tomography / Computed Tomography (SPECT/CT)
- High-Frequency Ultrasound (HFUS)
- Bioluminescence and fluorescence Imaging
- Photoacoustic imaging
- Multiphoton microscopy
- Intrinsic optical imaging
Specialized imaging of ex vivo/postmortem organs and tissues, of both humans and animals for high-resolution anatomical and molecular analysis.
Preclinical radiotherapy capabilities for targeted treatment studies and combination therapy research.
Facilities for evaluating learning, memory, motor function, and social behavior.
Courses and hands-on training in imaging techniques, data analysis, and animal handling.
Streamlined onboarding for external users through the European infrastructure.

Also see...

Infrastructure

See our imaging platforms and additional facilities for small animal imaging and behavioral research.

Collaborations

We actively collaborate with academic institutions, clinical departments, and industry across Europe and beyond.

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Collaborations

We actively collaborate with academic institutions, clinical departments, and industry across Europe and beyond. Our infrastructure supports a wide range of translational research projects.

More than 30% of the studies conducted within the center involve external collaborators, reflecting its commitment to open-access science and interdisciplinary innovation. As part of the Molecular Imaging Dutch Node of Euro-BioImaging, we offer structured access to facilities for researchers across Europe.

Collaboration opportunities include: