CD44-positive proliferating glomerular cells, most likely parietal epithelial cells, are essential in the pathogenesis of scarring glomerular disease.
In a recent publication in Kidney International a multidisciplinary team integrated by Jennifer Eymael and Bart Smeets, Dept. of Pathology and Johan van der Vlag, Dept. of Nephrology, theme Renal disorders, and collaborators from the Academic Medical Center, Amsterdam and the RWTH University of Aachen, Germany, has established novel molecular insights for understanding the role of parietal epithelial cells in the development of the typical glomerular lesions of crescentic glomerulonephritis and of glomerulosclerosis.
Related news items
A personal touch of Marlies Cornelissen31 October 2019
In order to promote interaction amongst colleagues within RIMLS, we have a ‘personal touch’ series setting employees in the spotlight. A light-hearted manner to learn about the colleagues you know and those you don’t. This week: Marlies Cornelissen.read more
Collective cancer invasion forms an integrin-dependent radioresistant niche29 October 2019
Anna Häger and Peter Friedl, theme Cancer development and immune defense, identified a new niche of cancer cell survival and developed an integrin inhibition therapy to overcome resistance. They have published their results in JEM.read more
Algorithm to predict which cancer patients benefit from immunotherapy29 October 2019
Rik Lindeboom and Michiel Vermeulen, theme Cancer development and immune defense, have developed an algorithm that can predict which cancer patients are more likely to benefit from immunotherapy. This new technology’s potential is described in Nature Genetics.read more
X² Ambition Award for Sandra Heskamp28 October 2019
This award is intended for 'coming women’: young, ambitious women at a stage of their careers where they make important career choices. This prize is especially for women who show exemplary behaviour within the organization where they work, but also outside their organization.read more
A personal touch of Mariya Chernyavska24 October 2019
In order to promote interaction amongst colleagues within RIMLS, we have a ‘personal touch’ series setting employees in the spotlight. A light-hearted manner to learn about the colleagues you know and those you don’t. This week: Mariya Chernyavska.read more