In European Journal of Preventive Cardiology Regina Konst and colleagues demonstrated that symptomatic women without obstructive coronary artery disease have a different pattern of risk factors and lower levels of psychosocial well-being compared with those with stable obstructive coronary artery disease.Background:
characterising patients with symptoms/signs of ischemic heart disease in the absence of obstructed coronary arteries (INOCA) remains challenging. Little is known about differences in risk factors and psychosocial well-being of these patients compared to those with stable angina due to obstructive coronary artery disease (CAD). Therefore, we evaluated patient characteristics in women with INOCA and women with CAD.
64 symptomatic women aged 40-65 years with INOCA and 64 age-matched symptomatic women with CAD completed questionnaires about traditional cardiovascular risk factors, non-traditional risk variables and psychosocial factors such as fatigue, cardiac anxiety, quality of life and anxiety/depression.
Results: no significant differences were found regarding most traditional cardiovascular risk factors. Of the non-traditional risk variables, women with INOCA more often had a history of rheumatic disorders (39% vs. 21%; p < 0,01) and premenopausal migraine (52% vs. 31%; p = 0,02) compared to women with CAD. Women with INOCA reported higher levels of fatigue (89,7 ± 25,3 vs. 76,4 ± 26,9, p < 0,01) and cardiac anxiety (1,5 ± 0,5 vs. 1,3 ± 0,5, p < 0,05) and lower levels of physical quality of life (34,3 ± 10,3 vs. 41,4 ± 10,2, p < 0,01) compared to women with CAD, all related to a higher symptom burden. Levels of anxiety and depression were overall low in both groups without significant differences.
women with INOCA have a different pattern of risk factors and experience more psychosocial distress – related to a higher symptom burden – compared to women with stable obstructive CAD.
Different cardiovascular risk factors and psychosocial burden in symptomatic women with and without obstructive coronary artery disease.
Konst RE, Elias-Smale SE, Lier A, Bode C, Maas AH.
Regina Konst is member of theme Vascular damage.
Related news items
Less registration leads to more time for the patient16 July 2020
On average, care providers spend more than 52 minutes of their working day on quality registrations. Only 36% of these registrations can be used to improve care and that the registration burden weighs on the motivation of care providers.read more
ATRO Medical, Radboudumc and Samaplast develop new meniscus prosthesis Consortium receives EUROSTARS grant for innovative project16 July 2020
An international consortium led by ATRO Medical, a spin-off of Radboudumc and DSM, will receive € 800,000 European funding for an innovation aimed at patients with knee osteoarthritis. These patients often suffer from cartilage wear due to a meniscus that no longer works properly.read more
First podcast 'AI for Life' about Artificial Intelligence in Nijmegen Podcast on medical image processing with Bram van Ginneken, Ritse Mann and Eva van Rikxoort16 July 2020
The first podcast on Artificial Intelligence (AI) in Nijmegen was released today. In this podcast on spotify and anchor Bram van Ginneken, Ritse Mann and Eva van Rikxoort talk about AI and medical image processing. The next podcast is about smart chatbots.read more
Cardiac Function in Relation to Myocardial Injury in Hospitalised Patients With COVID-1916 July 2020
In Netherlands Heart Journal RIHS researcher Frederik van den Heuvel described that in hospitalized COVID-19 patients, it seems that COVID-19 predominantly affects the respiratory system, while cardiac dysfunction occurs less often.read more
Registration for Social Dutch course for researchers opens soon14 July 2020
In September, a new course Social Dutch will start at Radboud In’to Languages. The course is very popular and the registration will open within 2 weeks. Keep an eye on the website in order to register in time!read more