4 April 2018

Circulating tumor DNA in esophageal and rectal cancer patients undergoing chemoradiation therapy

Hans de Wilt and  Bastiaan Klarenbeek, theme Tumors of the digestive tract, received a research grant of 80.000 euro from the 'Bergh in het Zadel' foundation to study circulating tumor DNA in their patients. Both surgeons are involved in the multimodality treatment of rectal and esophageal cancer patients and are interested in these 'liquid biopsies' during and after treatment. In close collaboration with Prof. Ligtenberg from the department of genetics, they will study circulating tumor DNA before the start of chemoradiation of these patients and compare this during and after treatment. The results might give insight in the response of the tumor on chemoradiation therapy, but also might reflect prognosis of patients after following surgical treatment.

Related news items


Cognitive behavioral therapy reduces severe fatigue in patients with advanced cancer during treatment

28 January 2020

In Annals of Oncology, RIHS researchers Hanneke Poort, Marlies Peters, Winette van der Graaf, Ria Nijhuis van der Sanden and colleagues showed significant effects of cognitive behavioral therapy on fatigue in patients with advanced cancer during treatment with palliative intent.

read more

RIMLS PhD retreat registration is open

23 January 2020

Yearly, RIMLS PhD candidates gather for the two-day PhD Retreat. Apart from the science, this event is highly valued for the opportunity to meet and get to know fellow PhD candidates during the social activities. Early bird registration and abstract submission deadline: 4 March 2020.

read more

First BeNeFit funding granted for psoriasis

17 January 2020

RIHS researchers Elke de Jong and Juul van den Reek of Dermatology Radboudumc and Dermatology Ghent received a grant of 1.6 million euros for investigating dose reduction of the newest biologics for psoriasis.

read more

Stofwisselkracht grant for Daan Panneman and Richard Rodenburg

16 January 2020

Daan Panneman & Richard Rodenburg have been awarded a Stofwisselkracht grant for their proposal “CRISPR/Cas9 knock-in complementation in fibroblasts of mitochondrial disease patients”. Together with Omar Tutakhel & Jan Smeitink they will investigate the possibility of using CRISPR/Cas9 knock-in.

read more

The PRIDE Study Evaluation of online methods of data collection

16 January 2020

In Paediatric and Perinatal Epidemiology RIHS researchers Marleen van Gelder and Nel Roeleveld described the recruitment methods and online data collection within the PRIDE Study, the largest Dutch birth cohort study.

read more

Laparoscopy reduces the number of adhesions but it is still too high

14 January 2020

Adhesions after abdominal surgery cause too many re-admissions. Although keyhole surgery reduces the number of adhesions and the complications associated with them, the total disease burden remains high, as reported in The Lancet by RIHS researcher Richard ten Broek and colleagues.

read more