go to main content
4 April 2018

Circulating tumor DNA in esophageal and rectal cancer patients undergoing chemoradiation therapy

Hans de Wilt and  Bastiaan Klarenbeek, theme Tumors of the digestive tract, received a research grant of 80.000 euro from the 'Bergh in het Zadel' foundation to study circulating tumor DNA in their patients. Both surgeons are involved in the multimodality treatment of rectal and esophageal cancer patients and are interested in these 'liquid biopsies' during and after treatment. In close collaboration with Prof. Ligtenberg from the department of genetics, they will study circulating tumor DNA before the start of chemoradiation of these patients and compare this during and after treatment. The results might give insight in the response of the tumor on chemoradiation therapy, but also might reflect prognosis of patients after following surgical treatment.

  • Want to know more about these subjects? Click on the buttons below for more news.

    Surgery

Related news items

What can we learn from rural Tanzanian food?

23 December 2021 What we eat affects our bodies. A diet high in plant based products and low in fat offers health benefits and prevents lifestyle diseases, such as cardiovascular disease. This is what Quirijn de Mast shows based on his research in Africa. read more

Freezer Challenge by Teun Bousema

13 April 2021 13 research groups, 1280 boxes discarded, 26% less energy consumption, and two winners. Watch our short video with the results of the Radboud Freezer Challenge. It is safe, and you can do it anytime. Warm up your freezers to cool down the planet! read more

Dutch Cancer Society grant for organ preservation study

1 October 2020 Hans de Wilt received a Dutch Cancer Society Grant of 625K euros for the STARTREC trial. The STARTREC trail is an international trial for patients with early cancer in the distal rectum read more

Increased role of patients after bowel cancer treatment

30 July 2020 Approximately 14,000 patients get colorectal cancer every year. Almost all patients are operated on and monitored afterwards (follow-up). In 2019 Radboudumc started a new approach to follow-up research after the treatment of stage II/III colorectal cancer. read more

Guiding the surgeon real-time tumor visualization during surgery

26 February 2020 Incomplete excision of tumor tissue negatively affects the prognosis of the patient. RIHS researcher Mark Rijpkema and colleagues are working on the development of new dual-labeled tracers and currently are implementing this into the clinic. read more

Laparoscopy reduces the number of adhesions but it is still too high

14 January 2020 Adhesions after abdominal surgery cause too many re-admissions. Although keyhole surgery reduces the number of adhesions and the complications associated with them, the total disease burden remains high, as reported in The Lancet by RIHS researcher Richard ten Broek and colleagues. read more