Tumors of the digestive tract About theme

In this research theme, we aim to improve prognosis and treatment of patients with tumors of the digestive tract, with a focus on sporadic and hereditary forms of colorectal and pancreatic cancer.

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Tumors of the digestive tract About theme

In this research theme, we aim to improve prognosis and treatment of patients with tumors of the digestive tract, with a focus on sporadic and hereditary forms of colorectal and pancreatic cancer. We aim to achieve better prevention of cancer in high-risk patients and develop and implement new diagnostic tools for staging and therapy response. In addition, we are working to create treatment innovations, ranging from improved surgical techniques to immunotherapy. Research into the etiology, epidemiology and genetics of these tumors will lead to improved primary, secondary and tertiary prevention.

Objectives

  • We will identify new genes responsible for hereditary colorectal cancer syndromes.
  • We will develop strategies for improving detection of hereditary forms of pancreatic cancer.
  • We aim to prevent cancer in high-risk patients using vaccination and lifestyle interventions.
  • We will develop new molecular diagnostic tools to predict tumor response to therapy.
  • We will identify relevant biomarkers for the development of metastatic disease and implement these factors in daily practice.
  • We will develop surgical techniques to optimize patient care.

Theme leader

Iris Nagtegaal MD PhD
full professor

+31 (024) 361 02 29

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Societal impact

More information will follow soon.

News and agenda

Organisation


Researchers Tumors of the digestive tract

See the researchers related to this theme.

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Centers of clinical expertise

Information might be only available in Dutch.


Answers in Dutch

Information on our research can also be found in Dutch on the Nationale Wetenschapsagenda website. The information here answers questions asked by Dutch citizens.

Nationale Wetenschapsagenda

Research group leaders

Affiliated institutes and centers

Radboud Institute for Health Sciences

Ideally, every procedure in clinical practice and public health should take place based on proof, instead of intuition or 'experience'. Our aim is to improve clinical practice and public health.

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Radboud Institute for Molecular Life Sciences

Our main aim is to achieve a greater understanding of the molecular mechanisms of disease. By integrating fundamental and clinical research, we obtain multifaceted knowledge of (patho)physiological processes.

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