NWO Domain Applied and Engineering Sciences (AES) has granted project ULTRA-X-TREME 4 million euros for developing new 3D ultrasound techniques allowing patient-specific diagnosis of vascular problems and prevention of unnecessary operations. The project is led by Chris de Korte, professor of Medical Ultrasound Techniques at Radboudumc and professor of Medical Ultrasound Imaging at the University of Twente.Vascular problems may have life-threatening consequences. For instance, ischemic cerebrovascular accidents are often caused by carotid artery atherosclerosis, and fatal rupture of the abdominal aorta often results from vascular wall weakening. Doctors may use echography to assess the risk of vascular complications by measuring the diameter of the vessels in question. However, this method is shown to have only limited predictive value. As a result, unnecessary and risky treatments are given, whereas high-risk cases remain unidentified.
As part of the program Ultrafast Ultrasound Imaging for Extended Diagnosis and Treatment of Vascular Disease (ULTRA-X-TREME), an international research team is to develop new and more accurate three-dimensional vascular wall and perfusion ultrasound imaging techniques. The team has been granted four million euros by the funding instrument Perspectief of NWO Domain AES. In the next five years, under the supervision of Chris de Korte, professor of Medical Ultrasound Techniques at Radboud university medical center and professor of Medical Ultrasound Imaging at the University of Twente, the researchers will develop new ultrasound sensors, contrast agents and analysis techniques to more accurately assess the necessity of vascular treatment.
The ULTRA-X-TREME consortium is a collaboration of hospitals, international industrial partners and Dutch research groups with a focus on ultrasound techniques and vascular biomechanics. In alphabetical order, the participants in the program are: ANSYS, Bracco Suisse S.A., Catharina Hospital, Erasmus MC, Harteraad, Mindray, Dutch Society for Vascular Surgery (NVvV), Philips Electronics Netherlands, Pie Medical Imaging, Radboud university medical center, Rijnstate Hospital, Delft University of Technology, Eindhoven University of Technology, TomTec Imaging Systems, University of Twente, Vermon S.A. and Verasonics.
Chris de Korte is member of theme Vascular damage.
Related news items
Social media posts on medication use during pregnancy often incorrect23 August 2019
Dutch social media regularly post about the safety of medicines for pregnant women. Many pregnant women use these posts as a source of information. A new analysis shows, however, that information found on social media about the risk of medication use often does not correspond with guidelines.read more
Hans van Bokhoven newly elected in Academia Europaea22 August 2019
The Academia Europaea is a functioning European Academy of Humanities, Letters and Sciences, composed of individual members.read more
Drug-induced interstitial lung disease in advanced breast cancer patients receiving everolimus22 August 2019
In Targeted Oncology, Annelieke Willemsen, Carla van Herpen and colleagues, showed that pulmonary function test with diffusion capacity of the lungs for carbon monoxide and serum biomarkers can be of aid to differentiate everolimus-related interstitial lung disease from other respiratory problems.read more
Publication in PNAS on dissecting EEC syndrome using single-cell RNA-seq22 August 2019
PhD candidates Eduardo Soares and Quan Xu in Jo Huiqing Zhou’s group in Molecular Developmental Biology, theme Reconstruction and regenerative medicine, have published a paper in PNAS on the disease mechanism of EEC syndrome using single-cell RNA-seq technology and patient-derived iPSCs.read more
Patient trust and participation in cell biological research21 August 2019
Alessandra Cambi and Gert Olthuis, discuss key ethical issues inherent in the development and the value of building trust and trustworthiness.read more
NWO grant for a tissue-generating patch to close diaphragmatic defects21 August 2019
Willeke Daamen and Toin van Kuppevelt, theme Reconstructive and regenerative medicine, were recently awarded a 690 k€ grant by NWO, domain Applied & Engineering Sciences, for the development of advanced patches for closure of diaphragmatic defects in children with congenital diaphragmatic hernia.read more