8 July 2019

CMBI, TML and Human Genetics organized a successful summerschool on 'Integrative X-omics Analyses Empowering Personalized Healthcare'.

The course coordinators professor Alain van Gool and professor Peter-Bram ‘t Hoen are looking back at an exciting week, in which 20 participants from all over Europe convened for a week full of lectures, practicals, and labtours. The week started with an introduction into biomarkers for personalized healthcare by Alain van Gool (TML). Marcel Nelen (Human Genetics) introduced them into novel genomics technologies, and Hans Wessels and Jolein Gloerich (TML) did the same for novel proteomics technologies. Peter-Bram ‘t Hoen presented a range of X-omics data integration strategies. Other topics like metabolomics, methylation and network-based data integration were covered by external speakers from the Netherlands X-omics Initiative.

Throughout the week, the participants worked on an assignment for which they needed to design a X-omics study, and define a data analysis and management plan. The participants worked in multidisciplinary teams of four. Their different scientific backgrounds helped to address this assignment from different angles. On Friday, the participants presented their exciting studies covering a range of different topics: from the study of the influence of microbiome on constipation in Parkinson's disease, to the identification of early marker signals for infection in rheumatoid arthritis patients after treatment with tocublizimab, risk assessment in prostate cancer based on combined imaging and -omics profiling, the molecular mechanisms of non-alcoholic fatty liver disease, and the early detection of cerebral course of disease in X-linked adrenoleukodystrophy.

The organizers are looking forward to a next edition.


More information about the program can be found here.

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