8 July 2019

CMBI, TML and Human Genetics organized a successful summerschool on 'Integrative X-omics Analyses Empowering Personalized Healthcare'.

The course coordinators professor Alain van Gool and professor Peter-Bram ‘t Hoen are looking back at an exciting week, in which 20 participants from all over Europe convened for a week full of lectures, practicals, and labtours. The week started with an introduction into biomarkers for personalized healthcare by Alain van Gool (TML). Marcel Nelen (Human Genetics) introduced them into novel genomics technologies, and Hans Wessels and Jolein Gloerich (TML) did the same for novel proteomics technologies. Peter-Bram ‘t Hoen presented a range of X-omics data integration strategies. Other topics like metabolomics, methylation and network-based data integration were covered by external speakers from the Netherlands X-omics Initiative.

Throughout the week, the participants worked on an assignment for which they needed to design a X-omics study, and define a data analysis and management plan. The participants worked in multidisciplinary teams of four. Their different scientific backgrounds helped to address this assignment from different angles. On Friday, the participants presented their exciting studies covering a range of different topics: from the study of the influence of microbiome on constipation in Parkinson's disease, to the identification of early marker signals for infection in rheumatoid arthritis patients after treatment with tocublizimab, risk assessment in prostate cancer based on combined imaging and -omics profiling, the molecular mechanisms of non-alcoholic fatty liver disease, and the early detection of cerebral course of disease in X-linked adrenoleukodystrophy.

The organizers are looking forward to a next edition.


More information about the program can be found here.

Related news items


4,8 million euros for prevention of tuberculosis among people with diabetes in Africa

16 July 2019

Reinout van Crevel and Lindsey te Brake have received European funding of 4.8 million euros to lead an international consortium to screen thousands of people with diabetes in Uganda and Tanzania for TB, and investigate the effect and costs of 3 months preventive treatment for TB.

read more

50.000 grant for Paul de Jonge and Harry Dolstra

15 July 2019

Paul de Jonge and Harry Dolstra, theme Cancer development and immune defense, received a €50.000,- (NWA-IDG) grant for their project regarding cancer immunotherapy.

read more

Handbook of biomarkers and precision medicine a new publication by Alain van Gool

12 July 2019

Alain van Gool published a new handbook on biomarkers and applications in (pre)clinical drug development for precision medicine.

read more

Summer greetings from René Bindels

5 July 2019

In this last newsletter before the summer break and before I wish you all a happy holiday, I would like to briefly summarize the first half of 2019 and especially look ahead to the interesting activities that will take place in the second half of the year.

read more

Prostate cancer theranostics imaging, surgical guidance, and targeted photodynamic therapy

5 July 2019

In Theranostics, Mark Rijpkema and colleagues present the development of a novel multimodal tracer that targets both preoperative imaging, surgical guidance, and targeted photodynamic therapy of PSMA-expressing prostate cancer.

read more

A personal touch of Huib Croes

4 July 2019

In order to promote interaction amongst colleagues within RIMLS, we have a ‘personal touch’ series setting employees in the spotlight. A light-hearted manner to learn about the colleagues you know and those you don’t. This week: Huib Croes.

read more