The research group led by researcher and general practitioner Erik Bischoff has received a ZonMw grant from the call ´Goed Gebruik Geneesmiddelen´ for study cardiovascular risk management.
The grant of over 680,000 euros is intended for research into cardiovascular risk management in people with antipsychotic drugs in general practice. Special is that in addition to this subsidy, the study also receives an in-kind contribution of 130,000 euros from the Arnhem care group Onze Huisartsen BV where the research takes place.
Erik Bischoff: 'The care group has developed a wonderful intervention in which general practitioners, psychiatrists, pharmacists and practice nurses work closely with patients with antipsychotics to reduce unnecessary medication use and reduce the increased risk of cardiovascular disease. In our TACTIC project we will first test this intervention on a small scale and then evaluate its effects and costs in a large experiment'.
The research forms the PhD trajectory for ELG framework doctor for cardiovascular diseases Kirsti Jakobs who played an important role in the development of the intervention. Her earlier research showed that people with severe mental illness (EPA) are estimated to die between eight and twenty years earlier than the general population, especially from cardiovascular diseases.
This ELG study, published in BMC Family Practice, shows that this group is only screened in 8.5%. Only in the case of diabetes mellitus does the annual screening reach 68.4%. People with EPA benefit from a customized cardiovascular risk management (CVRM), but are not yet mentioned in the standard CVRM of the Dutch Society of General Practitioners. Researcher and ELG PhD candidate Kirsti Jakobs: 'Our research also shows that in 68.3% of antipsychotic users no suitable EPA diagnosis was registered in the GP information system. This could be an indication that GPs often prescribe antipsychotics off-label, lack diagnostic information or register the wrong code. GPs are in a key position to proactively invite this vulnerable group to CVRM. It is recommended to be vigilant when prescribing antipsychotics off-label or not properly documented'.
Related news items
New ultra-high field MRI system available for Radboudumc and Radboud University10 June 2021
Recently, the Hahn institute in Essen has received a new heart: a 20-ton ultra-high-field MRI scanner from Siemens Healthcare with a magnetic field strength of 7 Tesla. The new CE-approved scanner is ready for business, and projects on body and brain imaging are starting up.read more
New method to prevent ovarian cancer increases quality of life8 June 2021
Researchers at Radboudumc have shown that quality of life is better in women with a BRCA1 or BRCA2 mutation after fallopian tube removal with delayed ovarian removal to prevent ovarian cancer.read more
Epidemiology and reporting characteristics of preclinical systematic reviews in PLoS Biology7 June 2021
Kim Wever, researcher of the department of Health Evidence and an international team published the article 'Epidemiology and reporting characteristics of preclinical systematic reviews' in PLoS Biology.read more
First Dutch professor of infectious disease outbreaks at Radboud university medical center4 June 2021
Chantal Bleeker-Rovers about research on coronavirus, Q fever and other infectious diseases outbreaksread more
European research project raises hopes in fight against rare diseases Solve-RD successfully established an innovative approach to jointly re-analyze genomic and phenotypic data from unsolved rare disease patients1 June 2021
For the first time in Europe hundreds of rare disease experts team up to actively share and jointly analyze existing data from unsolved rare disease patients.read more