16 December 2020

Together with scientists from Erasmus MC, Radboudumc has signed a license agreement with Sebia, world leader in multiple myeloma diagnostics. This partnership enables the development of an ultra-sensitive blood assay that can detect minimal residual disease (MRD) in myeloma patients to guide optimal personalized treatment. Currently, MRD status is assessed on bone marrow aspirates. However, bone marrow sampling is invasive and introduces the risk of non-representative sampling due to heterogenous disease spreading. The new personalized targeted mass spectrometry technology developed by Erasmus MC and Radboudumc allows MRD monitoring directly in serum of myeloma patients.

“Through personalized diagnostics on one drop of blood, we can create a patient-friendly alternative to monitor MRD in myeloma patients,” says principle investigator Hans Jacobs, Theme Cancer development and immune defense. “This allows dynamic monitoring of patients with deep responses, which is crucial for early detection of disease relapse. This assay will greatly support the path towards precision medicine in these patients.”

"In this approach we combine technology innovation with clinical impact by developing and applying truly personalized diagnostics for Multiple Myeloma care, a beautiful showcase of translational biomarker work by collaboration", says Alain van Gool, Theme Metabolic disorders.

read more

Related news items


New research through grants for Radboudumc researchers

14 January 2021

Several researchers at the Radboudumc have received grants to start new studies, including on rare diseases, liver disease and cancer metastases. These are grants from the Dutch Research Council, European Joint Programme on Rare Diseases and the Gastric Liver Disease Foundation.

read more

Should we prepare for a corona-related depression wave? Indira Tendolkar and Eric Ruhé talk about their research projects

13 January 2021

Since the outbreak of the SARS-CoV-2, many of us have been staying at home in order to limit our social interactions, to keep ourselves and others safe from the virus. Yet, there’s also concern about what social distancing and anxiety generated by media reports are doing to people's mental health.

read more

RIMLS online award ceremony proudly presenting the winners

13 January 2021

In this special webinar of the RIMLS New Year Celebration, scientific director René Bindels reviewed 2020 and looked forward to 2021. But more importantly a number of researchers received prizes in the traditional RIMLS awards ceremony. 

read more

Dutch Digestive Foundation grant for Joost Drenth

13 January 2021

Joost Drenth, theme Renal disorders, received a Dutch Digestive Foundation grant in cooperation with his colleagues from Amsterdam UMC and Leiden UMC.

read more

Cooling vests alleviate perceptual heat strain perceived by COVID-19 nurses

11 January 2021

Wearing cooling vests during a COVID-19 shift ensures that nurses experience less heat during their work. The cooling vests offer such effective cooling that they are now part of the standard work clothing for nurses in the COVID nursing departments at Radboudumc.

read more

Koen van den Dries received ENW-XS grant from the NWO

7 January 2021

Koen van den Dries has received an ENW-XS grant from the NWO for his project titled: Small differences, large impact: how actin variants differentially control cancer cell migration.

read more