This thesis includes four studies on prevalence and implications of geriatric syndromes and multimorbidity (chronic health conditions) in older patients with different psychiatric disorders and in different settings.
Two studies on medically unexplained symptoms (MUS) found that these symptoms are often not as unexplained as they seemed in older adults. MUS were frequently accompanied by frailty, multimorbidity and psychiatric disorders. This intermingling made recognition of these problems difficult.
Persons aged 80 and over, have little benefit from antidepressants when treated for a depressive disorder. Whether this is due to frailty, multimorbidity, undernutrition, functional impairment or cognitive dysfunction remains unclear, because the conducted systematic review showed that these characteristics were barely taken into account in treatment studies on depression in older adults and that persons aged 75 years and over, were underrepresented. This means that the results of these studies are not applicable to many of the patients whom doctors actually have to treat.
The last study found that older adults who were acutely admitted to geriatric psychiatric wards were often frail, undernourished and had a high level of multimorbidity. Frailty and multimorbidity were important factors in not being able to return home after discharge. Frailty also predicted mortality within five years after admission.
Overall, this thesis shows that geriatric problems are relevant and have implications for older adults with psychiatric disorders. It sheds new light on the connection between psychiatry, geriatrics and psychology and the necessity to integrate care for complex patients with psychiatric disorders.
Related news items
BRAINMODEL: precision medicine for brain disorders25 October 2021
A team of researchers from Radboudumc, VU Amsterdam and other institutes is going to look for new and better ways to heal developmental disorders in the brain.read more
How healthy is James Bond? - A flu to a kill No time to die: the pathogens surrounding secret agent 00721 October 2021
James Bond made a total of 25 films between 1962 and 2021. In all those films, secret agent 007 washed his hands only twice, even though he often stayed in not so hygienic places with considerable health risks. Radboudumc researchers examined all the health risks in the 47 countries Bond visited.read more
Surprisingly dominant cause underlying type I congenital defect of glycosylation21 October 2021
Alex Garanto, Melissa Bärenfänger, Mirian Janssen, and Dirk Lefeber published a new study, identifying a surprisingly dominant genetic cause underlying type I congenital defect of glycosylation with neuromusculoskeletal phenotypes.read more
Sensitive blood-test as a patient-friendly alternative for bone marrow-based cancer monitoring20 October 2021
Hans Jacobs and Pieter Langerhorst, theme Cancer development and immune defense, and colleagues are one step closer to implementation of personalized diagnostics for bone marrow-based cancer monitoring.read more
Register for peer coaching for RIMLS PhD candidates20 October 2021
As a PhD candidate, you are in the lead of your own learning process, but you don’t need to do this alone. Register for the peer-coaching group ‘Stay in the lead – Together’ before 11 November 2021.read more