29 July 2021

Jeroen de Baaij from the department of Physiology, theme Renal disorders obtained a Senior Kolff Fellowship from the Dutch Kidney Foundation (Nierstichting).

Jeroen's research proposal ‘Crystal Clear: Dietary prevention of vascular calcification in chronic kidney disease’ was awarded a Senior Kolff Fellowship of 375K Euro. In this project, Jeroen de Baaij aims to develop a dietary approach to prevent vascular calcification in chronic kidney disease. 

Cardiovascular disease is the most common cause of death in patients with chronic kidney disease (CKD). Already in early stages of kidney failure, the risk of cardiovascular disease is 2-fold higher than in individuals with a normal kidney function. Vascular calcification has been demonstrated to be a major contributor to cardiovascular morbidity and mortality in CKD.

In his Kolff senior project, Jeroen will examine the effects of individual nutrients on calcification and vascular function in cell models and in a large patient cohort. Subsequently, a balanced anti-calcification diet will be designed and tested in animal models of CKD. The research proposal is a collaborative effort with Gerjan Navis, Martin de Borst and Rozemarijn Vliegenthart from University Medical Center Groningen. 

The Dutch Kidney Foundation Kolff program aims to stimulate the quality of the renal scientific field in the Netherlands through providing personal grants that support all phases of a research career. The program establishes stronger links between research and patient care.

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